Date published: 2025-11-4

1-800-457-3801

SCBT Portrait Logo
Seach Input

Kanamycin acid sulfate (CAS 64013-70-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Kanamycin A
Application:
Kanamycin acid sulfate is a 70S ribosome interacting antibiotic
CAS Number:
64013-70-3
Molecular Weight:
680.65
Molecular Formula:
C18H36N4O112H2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Kanamycin acid sulfate is an aminoglycoside antibiotic that functions by inhibiting protein synthesis in bacteria. It achieves this by binding to the 30S subunit of the bacterial ribosome, thereby disrupting the translation process and leading to the production of faulty or incomplete proteins. This interference with protein synthesis ultimately results in the inhibition of bacterial growth and reproduction. Kanamycin acid sulfate′s mechanism of action involves the induction of mistranslation and the production of abnormal proteins, which leads to the disruption of cellular processes in susceptible bacteria. This antibiotic′s mechanism of action at the molecular level involves its interaction with the ribosomal subunit, preventing the accurate reading of genetic information and the synthesis of functional proteins.


Kanamycin acid sulfate (CAS 64013-70-3) References

  1. Identification and characterization of hsa, the gene encoding the sialic acid-binding adhesin of Streptococcus gordonii DL1.  |  Takahashi, Y., et al. 2002. Infect Immun. 70: 1209-18. PMID: 11854202
  2. Isolation of a dual plant promoter fragment from the Ti plasmid of Agrobacterium tumefaciens.  |  Velten, J., et al. 1984. EMBO J. 3: 2723-30. PMID: 16453574
  3. Behavior of RNAi suppressor protein 2b of Cucumber mosaic virus in planta in presence and absence of virus.  |  Praveen, S., et al. 2008. Virus Genes. 37: 96-102. PMID: 18438704
  4. Cloning of the citrate permease gene of Lactococcus lactis subsp. lactis biovar diacetylactis and expression in Escherichia coli.  |  Sesma, F., et al. 1990. Appl Environ Microbiol. 56: 2099-103. PMID: 2117878
  5. Synergistic anticancer activity of curcumin and catechin: an in vitro study using human cancer cell lines.  |  Manikandan, R., et al. 2012. Microsc Res Tech. 75: 112-6. PMID: 21780253
  6. Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering.  |  Gao, W., et al. 2017. PLoS One. 12: e0181971. PMID: 28753625
  7. Removal of the innocuity test from The International Pharmacopoeia and WHO recommendations for vaccines and biological products.  |  Lei, D., et al. 2020. Biologicals. 66: 17-20. PMID: 32536585
  8. Kanamycin Supplement for the Disaggregation of Platelet Clumps in EDTA-Dependent Pseudothrombocytopenia Specimens.  |  Tantanate, C., et al. 2022. Lab Med. 53: e69-e73. PMID: 34668538
  9. Agrobacterium-mediated transformation of protoplasts from oilseed rape (Brassica napus L.).  |  Thomzik, JE. 1995. Methods Mol Biol. 44: 71-8. PMID: 7581685
  10. Agrobacterium-mediated transformation of stem disks from oilseed rape (Brassica napus L.).  |  Thomzik, JE. 1995. Methods Mol Biol. 44: 79-85. PMID: 7581686
  11. Colorimetric evaluation of cultured osteoblast-like cells (ROS 17/2.8).  |  Genty, C., et al. 1994. Biotech Histochem. 69: 160-4. PMID: 8068810
  12. Highly presumptive identification of bacterial isolates associated with the recent Canada-wide mastitis epizootic as Nocardia farcinica.  |  Manninen, KI., et al. 1993. Can J Microbiol. 39: 635-41. PMID: 8364799
  13. Tobacco protoplast transformation and use for functional analysis of newly isolated genes and gene constructs.  |  Fischer, R. and Hain, R. 1995. Methods Cell Biol. 50: 401-10. PMID: 8531811

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Kanamycin acid sulfate, 1 g

sc-263433
1 g
$40.00

Kanamycin acid sulfate, 5 g

sc-263433A
5 g
$130.00