Molecular structure of Chlorin e6, CAS Number: 19660-77-6
Chlorin e6 (CAS 19660-77-6)
See product citations (22)
Alternate Names:
Chlorin e6 also known as (17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid
Application:
Chlorin e6 is a naturally occurring chlorin commonly used photosensitizer and can be used as a nanotechnology delivery tool
CAS Number:
19660-77-6
Molecular Weight:
596.68
Molecular Formula:
C34H36N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Chlorin e6 is a naturally occurring chlorin used as a photosensitizer. Chlorin e6 has been examined as a nanotechnology delivery tool. It is a promising compound for medical and scientific research due to its ability to selectively target and damage specific cells or tissues while leaving surrounding tissue unharmed. It has been used in cell culture studies to study the effects of reactive oxygen species (ROS) on cell viability and cell metabolism. Chlorin e6 has also been used in a variety of biochemical assays, such as enzyme-linked immunosorbent assays (ELISA) and Western blotting. Chlorin e6 may act to induce a variety of biological effects, such as cell death and gene activation. It has also been shown to induce apoptosis in cancer cells.
Chlorin e6 (CAS 19660-77-6) References
- Chlorin e6 Conjugated Methoxy-Poly(Ethylene Glycol)-Poly(D,L-Lactide) Glutathione Sensitive Micelles for Photodynamic Therapy. | Kumari, P., et al. 2020. Pharm Res. 37: 18. PMID: 31897768
- A photoactivatable antibody-Chlorin e6 conjugate enabling singlet oxygen production for tumor-targeting photodynamic therapy. | Pan, Q., et al. 2021. Biomed Mater. 16: PMID: 32584266
- Chlorin e6-mediated photodynamic therapy modulates adipocyte differentiation and lipogenesis in 3T3-L1 cells. | Ryu, AR., et al. 2020. Photodiagnosis Photodyn Ther. 31: 101917. PMID: 32659375
- Chlorin e6 embedded in phospholipid nanoparticles equipped with specific peptides: Interaction with tumor cells with different aminopeptidase N expression. | Torkhovskaya, TI., et al. 2021. Biomed Pharmacother. 134: 111154. PMID: 33360931
- Self-Activatable Photo-Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy. | Ding, J., et al. 2021. Adv Mater. 33: e2005562. PMID: 33432702
- Chlorin e6-1,3-diphenylisobenzofuran polymer hybrid nanoparticles for singlet oxygen-detection photodynamic abaltion. | Wang, XH., et al. 2021. Methods Appl Fluoresc. 9: 025003. PMID: 33524966
- Chlorin e6 conjugated chitosan as an efficient photoantimicrobial agent. | Yue, L., et al. 2021. Int J Biol Macromol. 183: 1309-1316. PMID: 34000311
- Photodynamic therapy using self-assembled nanogels comprising chlorin e6-bearing pullulan. | Kawasaki, R., et al. 2021. J Mater Chem B. 9: 6357-6363. PMID: 34286817
- Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells. | Ma, QL., et al. 2022. Photodiagnosis Photodyn Ther. 37: 102645. PMID: 34823034
- Chlorin e6-Biotin Conjugates for Tumor-Targeting Photodynamic Therapy. | Liu, W., et al. 2021. Molecules. 26: PMID: 34885922
- Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer. | Yu, TT., et al. 2022. J Cancer Res Clin Oncol. 148: 867-879. PMID: 34997349
- Water-soluble chlorin e6-hydroxypropyl chitosan as a high-efficiency photoantimicrobial agent against Staphylococcus aureus. | Yue, L., et al. 2022. Int J Biol Macromol. 208: 669-677. PMID: 35346676
- Preliminary low-dose photodynamic exposure to skin cancer with chlorin e6 photosensitizer. | Efendiev, KT., et al. 2022. Photodiagnosis Photodyn Ther. 38: 102894. PMID: 35490962
- Photodynamic Therapy with Chlorin e6 Derivative for Chronic Central Serous Chorioretinopathy (Pilot Study). | Kustryn, T., et al. 2022. J Ocul Pharmacol Ther. 38: 505-512. PMID: 35687410
- Chlorin e6: A Promising Photosensitizer in Photo-Based Cancer Nanomedicine. | Hak, A., et al. 2023. ACS Appl Bio Mater. 6: 349-364. PMID: 36700563
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chlorin e6, 100 mg | sc-263067 | 100 mg | $102.00 | |||
Chlorin e6, 250 mg | sc-263067A | 250 mg | $199.00 | |||
Chlorin e6, 1 g | sc-263067B | 1 g | $549.00 | |||
Chlorin e6, 5 g | sc-263067C | 5 g | $2199.00 |