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Cdc3 Antibody (yC-15): sc-26295

 |  Datasheet

(Based on data analysis)

  • Cdc3 Antibody (yC-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of Cdc3 of Saccharomyces cerevisiae origin
  • recommended for detection of Cdc3 of Saccaromyces cerevisiae origin by WB and ELISA
  • blocking peptide, sc-26295 P
 

See additional Cdc Antibodies including Cdc, Cdc2, Cdc3, CdcA3, Cdc4, CdcA4, Cdc5, Cdc6, Cdc7, Cdc10, Cdc11, Cdc13, Cdc14, Cdc14 Phosphatase, Cdc15, Cdc16, Cdc20, Cdc23, Cdc24, Cdc25, Cdc26, Cdc27, Cdc28, Cdc34, Cdc35, Cdc37, Cdc40, Cdc42, Cdc45, Cdc50, Cdc50C, Cdc53, Cdc123, Cdc42EP2, Cdc42EP4 and Cdc42EP5.

Ordering Information
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc3 Antibody (yC-15) sc-26295 200 µg/ml $279
Cdc3 (yC-15) P sc-26295 P
(peptide)
100 µg/0.5 ml $61


Yeast cell division control (Cdc) genes encode a highly conserved family of protein-serine/threonine/tyrosine kinases and phosphatases that are required for the execution of discrete steps in the cell cycle. In the budding yeast Saccharomyces cerevisiae, the Cdc3, Cdc10, Cdc11, Cdc12, and Sep7/Shs1 septins assemble early in the cell cycle in a ring that marks the cytokinetic plane throughout the budding cycle (1,2). This ring structure participates in different aspects of morphogenesis, such as selection of cell polarity, localization of chitin synthesis, the switch from hyperpolar to isotropic bud growth after bud emergence and the spatial regulation of septation (2). The septins are a major structural component of a set of filaments at the mother-bud neck and function in the formation of septa, mating projections, and spores in S. cerevisiae (1,3). Mutants, defective in any of the four genes (CDC3, CDC10, CDC11, CDC12), lack these septin filaments and display a pleiotropic phenotype that involves abnormal bud growth and an inability to complete cytokinesis (4). Specifically, the CDC3 and CDC12 septin genes are essential for viability (3). Cdc3 is a substrate of the cell cycle regulatory cyclin-dependent kinase (Cdk), Cdc28 (5). Two serines near the C-terminus of Cdc3 are phosphorylated in a Cdc28-dependent manner (5).