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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of TyrRS of human origin
- recommended for detection of TyrRS of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
- blocking peptide, sc-26209 P
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
YARS |
8565 |
1p35.1 |
NM_003680 |
P54577
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608323 |
| Mouse |
Yars |
107271 |
4 D2.2 |
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Q91WQ3
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N/A |
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TyrRS Background Information
Tryptophanyl-tRNA synthetases are essential enzymes that catalyze the aminoacylation of tRNA(Trp) with tryptophan, an essential function of the cell’s protein synthesis machinery. Two forms of tryptophanyl-tRNA synthetase exist; a cytoplasmic form, named TrpRS (also known as WARS), and a mitochondrial form, named WARS2. In normal cells, human TrpRS exists as a full length form and as a truncated form designated mini TrpRS, which is produced by alternative splicing. Expression of mini TrpRS is highly stimulated in human cells by the addition of IFN-g. Although both human full length TrpRS and mini TrpRS are enzymatically active in aminoacylation, they differ in angiostatic activity. The tyrosyl-tRNA synthetase (TyrRS), a protein related to TrpRS, exists as a homodimeric enzyme that catalyzes the aminoacylation of tRNA(Tyr) by L-tyrosine.
| TyrRS (C-18) Product Citations |
See how others have used TyrRS (C-18): sc-26209 antibody and or TyrRS (C-18) antibody conjugates.
1 total citations Loading citations.
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TyrRS (C-18)
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TyrRS (C-18): sc-26209. Western blot analysis of TyrRS expression in non-transfected 293: sc-110760 (A), human TyrRS transfected 293: sc-113365 (B) and HeLa (C) whole cell lysates. TyrRS (C-18): sc-26209. Western blot analysis of TyrRS expression in non-transfected 293T: sc-117752 (A), mouse TyrRS transfected 293T: sc-126170 (B) and HeLa (C) whole cell lysates. TyrRS (C-18): sc-26209. Western blot analysis of TyrRS expression in non-transfected 293T: sc-117752 (A), mouse TyrRS transfected 293T: sc-126172 (B) and HeLa (C) whole cell lysates. TyrRS (C-18): sc-26209. Western blot analysis of TyrRS expression in non-transfected 293T: sc-117752 (A), mouse TyrRS transfected 293T: sc-126171 (B) and HeLa (C) whole cell lysates. |
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