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home » Signaling Intermediates » Cbl Antibody / Cbl Antibodies » p-Cbl (Tyr 700)-R: sc-26140-R

p-Cbl (Tyr 700)-R Antibody: sc-26140-R

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • recommended for detection of Tyr 700 phosphorylated Cbl of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, bovine and porcine
  • blocking peptide, sc-26140 P
 
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Ordering InformationProduct Citations
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-Cbl (Tyr 700) P sc-26140 P
(peptide)
 100 µg/0.5 ml $61
p-Cbl (Tyr 700)-R sc-26140-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100,000 units $462
Lambda Phosphatase sc-200312A 20,000 units $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cbl siRNA (h) sc-29242 10 µM $258
Cbl siRNA (m) sc-29949 10 µM $258
Cbl (h)-PR sc-29242-PR 10 µM $23
Cbl (m)-PR sc-29949-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cbl shRNA Plasmid (h) sc-29242-SH 20 µg $520
Cbl shRNA Plasmid (m) sc-29949-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cbl shRNA (h) Lentiviral Particles sc-29242-V 200 µl $625
Cbl shRNA (m) Lentiviral Particles sc-29949-V 200 µl $625

Cbl Background Information
The c-Cbl proto-oncogene has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas-Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis. The c-Cbl gene product has been identified as a cytoplasmic protein with apparent DNA binding and dimerization domains characteristic of transcription factors. A single c-Cbl locus termed CBL2 has been mapped to human chromosome 11q23. This region of chromosome 11 is involved in translocations and deletions in a broad range of leukemias; c-Cbl has been found to be translocated from chromosome 11 in leukemias with either t(4;11) or t(11;14) abnormalities.

p-Cbl (Tyr 700)-R Product Citations
See how others have used p-Cbl (Tyr 700)-R: sc-26140-R antibody and or p-Cbl (Tyr 700)-R antibody conjugates.


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p-Cbl (Tyr 700)-R
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sc-26140-R
p-Cbl (Tyr 700)-R: sc-26140-R. Western blot analysis of Cbl phosphorylation in untreated (A), pervanadate treated (B) and pervanadate and lambda protein phosphatase treated (C) Jurkat whole cell lysates.
sc-26140-R
Western blot analysis of c-Cbl phosphorylation in untreated (A, D), prevanadate treated (B, E) and prevanadate and lambda protein phosphatase treated (C, F) Jurkat whole cell lysates. Antibodies tested include p-Cbl (Tyr 700)-R: sc-26140-R (A, B, C) and Cbl (A-9): sc-1651 (D, E, F).
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