Molecular structure of XTT sodium salt, CAS Number: 111072-31-2
XTT sodium salt (CAS 111072-31-2)
See product citations (9)
Alternate Names:
X4626; 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt
Application:
XTT sodium salt is used in an assay for cell viability and cell proliferation
CAS Number:
111072-31-2
Molecular Weight:
673.52
Molecular Formula:
C22H16N7O13S2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
XTT sodium salt is a tetrazolium sodium salt that can be used in the XTT assay for cell viablilty and cell proliferation. The reactions involving XTT sodium salt will result in the formation of a soluble formazan dye, an advantage over the use of MTT due to MTT requiring a solubilization step. another advantage of XTT sodium salt is higher sensitivity and greater dynamic range over MTT. XTT sodium salt has displayed applicability in monitoring biologcially active products with superoxide anion participation in DNA scission. The compound has also been used to asses valvular injury for testing cryopreserved cardiac valves.
XTT sodium salt (CAS 111072-31-2) References
- Relationship between the reduction of tetrazolium salt XTT and DNA strand breakage with aminosugars. | Shimamura, T., et al. 2000. J Agric Food Chem. 48: 1204-9. PMID: 10775373
- Role for cell density in antifungal drug resistance in Candida albicans biofilms. | Perumal, P., et al. 2007. Antimicrob Agents Chemother. 51: 2454-63. PMID: 17502416
- An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. | Roehm, NW., et al. 1991. J Immunol Methods. 142: 257-65. PMID: 1919029
- Short Culture of Bovine Hepatocytes Biopsied from Dairy Cows as a Model for Toxicological Studies-CYP 1A1 Activity Response to Zearalenone Treatment. | Barć, J., et al. 2023. Int J Mol Sci. 24: PMID: 37569719
- Sub-lethal concentrations of chlorhexidine inhibit Candida albicans growth by disrupting ROS and metal ion homeostasis. | Jiang, Q., et al. 2023. J Oral Microbiol. 15: 2278937. PMID: 38415078
- Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators. | Wang, Z., et al. 2024. Sci Adv. 10: eadj1468. PMID: 38718125
- Comparison of Physicochemical, Antioxidant, and Cytotoxic Properties of Caffeic Acid Conjugates. | Świderski, G., et al. 2024. Materials (Basel). 17: PMID: 38893840
- XTT-colorimetric assay as a marker of viability in cryoprocessed cardiac valve. | Lu, JH., et al. 1997. J Mol Cell Cardiol. 29: 1189-94. PMID: 9160870
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
XTT sodium salt, 100 mg | sc-258336 | 100 mg | $310.00 |