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Tubercidin (CAS 69-33-0)

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Application:An inhibitor of multiple metabolic processes such as RNA processing, nucleic acid synthesis, & protein synthesis
CAS Number:69-33-0
Purity:>99%
Molecular Weight:266.25
Molecular Formula:C11H14N4O4
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Tubercidin sc-258322 10 mg $137
Tubercidin sc-258322A 50 mg $555
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Description
Toxic adenosine analog with antiviral,antitrypanosomal, and antifungal functions. Inhibits multiple metabolic processes which includes: RNA processing, nucleic acid synthesis, protein synthesis, and methylation of tRNA through intracellular incorporation into nucleic acids. Acts as a plant antifungal, inhibits mammalian SAH hydrolase (SAHH), and blocks purine biosynthesis in Candida famata.
Technical Information
Appearance:White crystalline
Derived from:Streptomyces tubercidicus
Storage:Store at 4° C
Safety and Reference Information
Transport:UN 3462
WGK Germany:3
RTECS:UY8870000
PubChem CID:5604
MDL Number:MFCD00056012
EC Number:200-703-4
Beilstein Registry:38498
SMILES:C1=CN(C2=C1C(=NC=N2)N)C3C(C(C(O3)CO)O)O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Acs, G., et al. 1964. Proc. Natl. Acad. Sci. U.S.A. 52: 493-501. PMID: 14206615
2. el Kouni, M.H., et al. 1983. Proc. Natl. Acad. Sci. U.S.A. 80: 6667-6670. PMID: 6579551
3. Fabianowska-Majewska, K., et al. 1994. Biochem. Pharmacol. 48: 897-903. PMID: 8093102
4. Stahmann, K.P., et al. 2000. Appl. Microbiol. Biotechnol. 53: 509-516. PMID: 10855708
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