Date published: 2026-7-4

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TACE Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of TACE Antibodies for advanced research in cell signaling and inflammation. Monoclonal TACE Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TACE, or TNF-alpha converting enzyme, plays a critical role in the processing of pro-inflammatory cytokines, particularly tumor necrosis factor-alpha (TNF-α). By regulating the availability of TNF-α, TACE is essential for maintaining immune homeostasis and mediating inflammatory responses. Dysregulation of TACE activity has been implicated in various pathological conditions, including autoimmune diseases and cancer, making TACE a significant target for therapeutic intervention. Understanding TACE function and regulation is crucial for developing new therapeutic approaches in inflammatory diseases. Researchers can utilize specific detection methods to examine TACE expression patterns in different tissue types and cellular compartments. Advanced imaging techniques combined with TACE monoclonal antibodies enable detailed visualization of protein localization and trafficking. Santa Cruz Biotechnology monoclonal TACE Antibodies support researchers worldwide in advancing our understanding of inflammatory processes and potential therapeutic applications.

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TACE Antibodies

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TACE/ADAM17 Antibody (B-6)

sc-390859mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAh
21
(15)

TACE siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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TACE/ADAM17 siRNA (h)

sc-36604hGene SilencingN/A
22
(0)

TACE/ADAM17 shRNA Plasmid (h)

sc-36604-SHhGene SilencingPuromycin
22
(0)

TACE/ADAM17 shRNA (h) Lentiviral Particles

sc-36604-VhGene SilencingPuromycin
22
(0)

TACE/ADAM17 siRNA (m)

sc-36605mGene SilencingN/A
3
(0)

TACE/ADAM17 shRNA Plasmid (m)

sc-36605-SHmGene SilencingPuromycin
3
(0)

TACE/ADAM17 shRNA (m) Lentiviral Particles

sc-36605-VmGene SilencingPuromycin
3
(0)

TACE CRISPR Knockout (KO) and HDR Plasmids

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TACE/ADAM17 CRISPR/Cas9 KO Plasmid (h2)

sc-400827-KO-2Gene Knockouth0
(0)

TACE/ADAM17 HDR Plasmid (h2)

sc-400827-HDR-2Homology Directed Repairh0
(0)

TACE/ADAM17 CRISPR/Cas9 KO Plasmid (m2)

sc-418985-KO-2Gene Knockoutm0
(0)

TACE/ADAM17 HDR Plasmid (m2)

sc-418985-HDR-2Homology Directed Repairm0
(0)

TACE CRISPR Double Nickase Plasmids

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TACE/ADAM17 Double Nickase Plasmid (h)

sc-400827-NICGene Knockouth0
(0)

TACE/ADAM17 Double Nickase Plasmid (h2)

sc-400827-NIC-2Gene Knockouth0
(0)

TACE/ADAM17 Double Nickase Plasmid (m)

sc-418985-NICGene Knockoutm0
(0)

TACE CRISPR Activation Plasmids and Lentiviral Particles

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TACE/ADAM17 CRISPR Activation Plasmid (h)

sc-400827-ACTGene Activationh0
(0)

TACE/ADAM17 CRISPR Activation Plasmid (h2)

sc-400827-ACT-2Gene Activationh0
(0)