IRF-1 Gel Shift Oligonucleotides: sc-2575

IRF-1 Gel Shift Oligonucleotides are short DNA sequences meticulously designed for use in gel shift assays, a foundational technique in molecular biology research aimed at scrutinizing protein-DNA interactions. The designation IRF-1 refers to Interferon Regulatory Factor 1 (IRF-1), a crucial transcription factor involved in the regulation of interferon-stimulated genes and various cellular processes, including immune response, apoptosis, and tumor suppression. Upon activation by interferons, IRF-1 translocates to the nucleus and binds to specific DNA sequences, known as IRF-1 binding sites, within the promoters of target genes, thereby modulating their transcriptional activity. By employing IRF-1 Gel Shift Oligonucleotides in gel shift assays, researchers can explore the binding kinetics, specificity, and affinity of IRF-1 to its target DNA sequences under diverse experimental conditions. This technique enables the elucidation of the molecular mechanisms underlying IRF-1-mediated gene regulation and provides insights into the complex signaling networks governing cellular responses to interferon signaling.