Date published: 2025-10-26

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PAI Antibodies

Santa Cruz Biotechnology features a diverse variety of PAI Antibodies for advanced research in the field of protease inhibition. PAI Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Plasminogen activator inhibitor (PAI) plays a crucial role in regulating fibrinolysis by inhibiting tissue-type and urokinase-type plasminogen activators. This regulation is vital for maintaining hemostasis and preventing excessive bleeding, making PAI an important target in studies related to cardiovascular diseases, cancer, and other pathological conditions. Understanding the function and regulation of PAI can provide insights into therapeutic strategies for various disorders. PAI research has revealed significant implications in wound healing, tissue remodeling, and vascular development. Ongoing studies continue to uncover new roles of PAI in cellular signaling pathways and disease progression. Recent findings highlight PAI's involvement in inflammatory responses and metabolic regulation. Santa Cruz Biotechnology monoclonal antibodies for PAI research support scientists worldwide in advancing our understanding of disease mechanisms and potential therapeutic approaches.

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PAI Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PAI-1/SERPINE1 Antibody (C-9)

sc-5297mouse IgG2b κ24-158 (h)WB, IP, IF, IHC(P), ELISAh
122
(23)

PAI-1/SERPINE1 Antibody (3A120)

sc-59633mouse IgGFL (h)WB, IP, ELISAh
7
(3)

PAI-2 Antibody (E-1)

sc-166539mouse IgG2a κ61-130 (h)WB, IP, IF, ELISAm, r, h
1
(3)

PAI-RBP1 Antibody (F-8)

sc-376832mouse IgG2a κ139-173 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(4)

PAI-RBP1 Antibody (1B9)

sc-100800mouse IgG1 κ1-403 (h)WB, IP, IF, ELISAm, r, h
2
(5)

PAI CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAI-RBP1 CRISPR/Cas9 KO Plasmid (h)

sc-418510hGene KnockoutGFP0
(0)

PAI-RBP1 HDR Plasmid (h)

sc-418510-HDRhHomology Directed RepairPuromycin0
(0)

PAI-RBP1 Double Nickase Plasmid (h)

sc-418510-NIChGene KnockoutPuromycin0
(0)

PAI-RBP1 Double Nickase Plasmid (h2)

sc-418510-NIC-2hGene KnockoutPuromycin0
(0)

PAI-RBP1 CRISPR/Cas9 KO Plasmid (m)

sc-426238mGene KnockoutGFP0
(0)

PAI-RBP1 HDR Plasmid (m)

sc-426238-HDRmHomology Directed RepairPuromycin0
(0)

PAI-RBP1 Double Nickase Plasmid (m)

sc-426238-NICmGene KnockoutPuromycin0
(0)

PAI-RBP1 Double Nickase Plasmid (m2)

sc-426238-NIC-2mGene KnockoutPuromycin0
(0)

PAI-2 CRISPR/Cas9 KO Plasmid (h)

sc-402054hGene KnockoutGFP0
(0)

PAI-2 HDR Plasmid (h)

sc-402054-HDRhHomology Directed RepairPuromycin0
(0)

PAI-2 Double Nickase Plasmid (h)

sc-402054-NIChGene KnockoutPuromycin0
(0)

PAI-2 Double Nickase Plasmid (h2)

sc-402054-NIC-2hGene KnockoutPuromycin0
(0)

PAI-2 CRISPR/Cas9 KO Plasmid (m)

sc-422288mGene KnockoutGFP0
(0)

PAI-2 HDR Plasmid (m)

sc-422288-HDRmHomology Directed RepairPuromycin0
(0)

PAI-2 Double Nickase Plasmid (m)

sc-422288-NICmGene KnockoutPuromycin0
(0)

PAI-2 Double Nickase Plasmid (m2)

sc-422288-NIC-2mGene KnockoutPuromycin0
(0)

PAI-3 CRISPR/Cas9 KO Plasmid (h)

sc-407725hGene KnockoutGFP0
(0)

PAI-3 HDR Plasmid (h)

sc-407725-HDRhHomology Directed RepairPuromycin0
(0)

PAI-3 Double Nickase Plasmid (h)

sc-407725-NIChGene KnockoutPuromycin0
(0)

PAI-3 Double Nickase Plasmid (h2)

sc-407725-NIC-2hGene KnockoutPuromycin0
(0)

PAI-3 CRISPR/Cas9 KO Plasmid (m)

sc-435264mGene KnockoutGFP0
(0)

PAI-3 HDR Plasmid (m)

sc-435264-HDRmHomology Directed RepairPuromycin0
(0)

PAI-3 Double Nickase Plasmid (m)

sc-435264-NICmGene KnockoutPuromycin0
(0)

PAI-3 Double Nickase Plasmid (m2)

sc-435264-NIC-2mGene KnockoutPuromycin0
(0)

PAI-1/SERPINE1 CRISPR/Cas9 KO Plasmid (h)

sc-400300hGene KnockoutGFP0
(0)

PAI-1/SERPINE1 HDR Plasmid (h)

sc-400300-HDRhHomology Directed RepairPuromycin0
(0)

PAI-1/SERPINE1 Double Nickase Plasmid (h)

sc-400300-NIChGene KnockoutPuromycin0
(0)

PAI-1/SERPINE1 Double Nickase Plasmid (h2)

sc-400300-NIC-2hGene KnockoutPuromycin0
(0)

PAI-1/SERPINE1 Double Nickase Plasmid (m)

sc-422287-NICmGene KnockoutPuromycin0
(0)

PAI-1/SERPINE1 Double Nickase Plasmid (m2)

sc-422287-NIC-2mGene KnockoutPuromycin0
(0)

PAI CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAI-RBP1 CRISPR Activation Plasmid (h)

sc-418510-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 CRISPR Activation Plasmid (h2)

sc-418510-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 Lentiviral Activation Particles (h)

sc-418510-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 Lentiviral Activation Particles (h2)

sc-418510-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 CRISPR Activation Plasmid (m)

sc-426238-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 CRISPR Activation Plasmid (m2)

sc-426238-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 Lentiviral Activation Particles (m)

sc-426238-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAI-RBP1 Lentiviral Activation Particles (m2)

sc-426238-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 CRISPR Activation Plasmid (h)

sc-402054-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 CRISPR Activation Plasmid (h2)

sc-402054-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 Lentiviral Activation Particles (h)

sc-402054-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 Lentiviral Activation Particles (h2)

sc-402054-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 CRISPR Activation Plasmid (m)

sc-422288-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 CRISPR Activation Plasmid (m2)

sc-422288-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 Lentiviral Activation Particles (m)

sc-422288-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAI-2 Lentiviral Activation Particles (m2)

sc-422288-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 CRISPR Activation Plasmid (h)

sc-407725-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 CRISPR Activation Plasmid (h2)

sc-407725-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 Lentiviral Activation Particles (h)

sc-407725-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 Lentiviral Activation Particles (h2)

sc-407725-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 CRISPR Activation Plasmid (m)

sc-435264-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 CRISPR Activation Plasmid (m2)

sc-435264-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 Lentiviral Activation Particles (m)

sc-435264-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAI-3 Lentiviral Activation Particles (m2)

sc-435264-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 CRISPR Activation Plasmid (h)

sc-400300-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 CRISPR Activation Plasmid (h2)

sc-400300-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 Lentiviral Activation Particles (h)

sc-400300-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 Lentiviral Activation Particles (h2)

sc-400300-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 CRISPR Activation Plasmid (m)

sc-422287-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 CRISPR Activation Plasmid (m2)

sc-422287-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 Lentiviral Activation Particles (m)

sc-422287-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAI-1/SERPINE1 Lentiviral Activation Particles (m2)

sc-422287-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAI siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAI-RBP1 siRNA (h)

sc-88846hGene SilencingN/A0
(0)

PAI-RBP1 shRNA Plasmid (h)

sc-88846-SHhGene SilencingPuromycin0
(0)

PAI-RBP1 shRNA (h) Lentiviral Particles

sc-88846-VhGene SilencingPuromycin0
(0)

PAI-RBP1 siRNA (m)

sc-151994mGene SilencingN/A0
(0)

PAI-RBP1 shRNA Plasmid (m)

sc-151994-SHmGene SilencingPuromycin0
(0)

PAI-RBP1 shRNA (m) Lentiviral Particles

sc-151994-VmGene SilencingPuromycin0
(0)

PAI-2 siRNA (h)

sc-40804hGene SilencingN/A0
(0)

PAI-2 shRNA Plasmid (h)

sc-40804-SHhGene SilencingPuromycin0
(0)

PAI-2 shRNA (h) Lentiviral Particles

sc-40804-VhGene SilencingPuromycin0
(0)

PAI-2 siRNA (m)

sc-40805mGene SilencingN/A
2
(0)

PAI-2 shRNA Plasmid (m)

sc-40805-SHmGene SilencingPuromycin
2
(0)

PAI-2 shRNA (m) Lentiviral Particles

sc-40805-VmGene SilencingPuromycin
2
(0)

PAI-3 siRNA (h)

sc-45416hGene SilencingN/A0
(0)

PAI-3 shRNA Plasmid (h)

sc-45416-SHhGene SilencingPuromycin0
(0)

PAI-3 shRNA (h) Lentiviral Particles

sc-45416-VhGene SilencingPuromycin0
(0)

PAI-3 siRNA (m)

sc-45417mGene SilencingN/A0
(0)

PAI-3 shRNA Plasmid (m)

sc-45417-SHmGene SilencingPuromycin0
(0)

PAI-3 shRNA (m) Lentiviral Particles

sc-45417-VmGene SilencingPuromycin0
(0)

PAI-1/SERPINE1 siRNA (h)

sc-36179hGene SilencingN/A
22
(0)

PAI-1/SERPINE1 shRNA Plasmid (h)

sc-36179-SHhGene SilencingPuromycin
22
(0)

PAI-1/SERPINE1 shRNA (h) Lentiviral Particles

sc-36179-VhGene SilencingPuromycin
22
(0)

PAI-1/SERPINE1 siRNA (m)

sc-36180mGene SilencingN/A
9
(0)

PAI-1/SERPINE1 shRNA Plasmid (m)

sc-36180-SHmGene SilencingPuromycin
9
(0)

PAI-1/SERPINE1 shRNA (m) Lentiviral Particles

sc-36180-VmGene SilencingPuromycin
9
(0)

PAI-1/SERPINE1 siRNA (r)

sc-60075rGene SilencingN/A0
(0)

PAI-1/SERPINE1 shRNA Plasmid (r)

sc-60075-SHrGene SilencingPuromycin0
(0)

PAI-1/SERPINE1 shRNA (r) Lentiviral Particles

sc-60075-VrGene SilencingPuromycin0
(0)