Date published: 2026-7-3

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PAI Antibodies

Santa Cruz Biotechnology features a diverse variety of PAI Antibodies for advanced research in the field of protease inhibition. PAI Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Plasminogen activator inhibitor (PAI) plays a crucial role in regulating fibrinolysis by inhibiting tissue-type and urokinase-type plasminogen activators. This regulation is vital for maintaining hemostasis and preventing excessive bleeding, making PAI an important target in studies related to cardiovascular diseases, cancer, and other pathological conditions. Understanding the function and regulation of PAI can provide insights into therapeutic strategies for various disorders. PAI research has revealed significant implications in wound healing, tissue remodeling, and vascular development. Ongoing studies continue to uncover new roles of PAI in cellular signaling pathways and disease progression. Recent findings highlight PAI's involvement in inflammatory responses and metabolic regulation. Santa Cruz Biotechnology monoclonal antibodies for PAI research support scientists worldwide in advancing our understanding of disease mechanisms and potential therapeutic approaches.

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PAI Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PAI-1/SERPINE1 Antibody (C-9)

sc-5297mouse IgG2b κ24-158 (h)WB, IP, IF, IHC(P), ELISAh
122
(23)

PAI-1/SERPINE1 Antibody (3A120)

sc-59633mouse IgGFL (h)WB, IP, ELISAh
7
(3)

PAI-2 Antibody (E-1)

sc-166539mouse IgG2a κ61-130 (h)WB, IP, IF, ELISAm, r, h
1
(3)

PAI-RBP1 Antibody (F-8)

sc-376832mouse IgG2a κ139-173 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(4)

PAI-RBP1 Antibody (1B9)

sc-100800mouse IgG1 κ1-403 (h)WB, IP, IF, ELISAm, r, h
2
(5)

PAI siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAI-RBP1 siRNA (h)

sc-88846hGene SilencingN/A0
(0)

PAI-RBP1 shRNA Plasmid (h)

sc-88846-SHhGene SilencingPuromycin0
(0)

PAI-RBP1 shRNA (h) Lentiviral Particles

sc-88846-VhGene SilencingPuromycin0
(0)

PAI-RBP1 siRNA (m)

sc-151994mGene SilencingN/A0
(0)

PAI-RBP1 shRNA Plasmid (m)

sc-151994-SHmGene SilencingPuromycin0
(0)

PAI-RBP1 shRNA (m) Lentiviral Particles

sc-151994-VmGene SilencingPuromycin0
(0)

PAI-2 siRNA (h)

sc-40804hGene SilencingN/A0
(0)

PAI-2 shRNA Plasmid (h)

sc-40804-SHhGene SilencingPuromycin0
(0)

PAI-2 shRNA (h) Lentiviral Particles

sc-40804-VhGene SilencingPuromycin0
(0)

PAI-2 siRNA (m)

sc-40805mGene SilencingN/A
2
(0)

PAI-2 shRNA Plasmid (m)

sc-40805-SHmGene SilencingPuromycin
2
(0)

PAI-2 shRNA (m) Lentiviral Particles

sc-40805-VmGene SilencingPuromycin
2
(0)

PAI-3 siRNA (h)

sc-45416hGene SilencingN/A0
(0)

PAI-3 shRNA Plasmid (h)

sc-45416-SHhGene SilencingPuromycin0
(0)

PAI-3 shRNA (h) Lentiviral Particles

sc-45416-VhGene SilencingPuromycin0
(0)

PAI-3 siRNA (m)

sc-45417mGene SilencingN/A0
(0)

PAI-3 shRNA Plasmid (m)

sc-45417-SHmGene SilencingPuromycin0
(0)

PAI-3 shRNA (m) Lentiviral Particles

sc-45417-VmGene SilencingPuromycin0
(0)

PAI-1/SERPINE1 siRNA (h)

sc-36179hGene SilencingN/A
22
(0)

PAI-1/SERPINE1 shRNA Plasmid (h)

sc-36179-SHhGene SilencingPuromycin
22
(0)

PAI-1/SERPINE1 shRNA (h) Lentiviral Particles

sc-36179-VhGene SilencingPuromycin
22
(0)

PAI-1/SERPINE1 siRNA (m)

sc-36180mGene SilencingN/A
9
(0)

PAI-1/SERPINE1 shRNA Plasmid (m)

sc-36180-SHmGene SilencingPuromycin
9
(0)

PAI-1/SERPINE1 shRNA (m) Lentiviral Particles

sc-36180-VmGene SilencingPuromycin
9
(0)

PAI-1/SERPINE1 siRNA (r)

sc-60075rGene SilencingN/A0
(0)

PAI-1/SERPINE1 shRNA Plasmid (r)

sc-60075-SHrGene SilencingPuromycin0
(0)

PAI-1/SERPINE1 shRNA (r) Lentiviral Particles

sc-60075-VrGene SilencingPuromycin0
(0)

PAI CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PAI-RBP1 CRISPR/Cas9 KO Plasmid (h)

sc-418510Gene Knockouth0
(0)

PAI-RBP1 HDR Plasmid (h)

sc-418510-HDRHomology Directed Repairh0
(0)

PAI-RBP1 CRISPR/Cas9 KO Plasmid (m)

sc-426238Gene Knockoutm0
(0)

PAI-RBP1 HDR Plasmid (m)

sc-426238-HDRHomology Directed Repairm0
(0)

PAI-1/SERPINE1 CRISPR/Cas9 KO Plasmid (h)

sc-400300Gene Knockouth0
(0)

PAI-1/SERPINE1 HDR Plasmid (h)

sc-400300-HDRHomology Directed Repairh0
(0)

PAI CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PAI-2 Double Nickase Plasmid (h)

sc-402054-NICGene Knockouth0
(0)

PAI-2 Double Nickase Plasmid (h2)

sc-402054-NIC-2Gene Knockouth0
(0)

PAI-1/SERPINE1 Double Nickase Plasmid (m)

sc-422287-NICGene Knockoutm0
(0)

PAI-1/SERPINE1 Double Nickase Plasmid (m2)

sc-422287-NIC-2Gene Knockoutm0
(0)

PAI CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PAI-2 CRISPR Activation Plasmid (h)

sc-402054-ACTGene Activationh0
(0)

PAI-1/SERPINE1 CRISPR Activation Plasmid (h)

sc-400300-ACTGene Activationh0
(0)

PAI-1/SERPINE1 CRISPR Activation Plasmid (m2)

sc-422287-ACT-2Gene Activationm0
(0)