 |
- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 1321-1400 of NCoA-3 of human origin
- recommended for detection of NCoA-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- TransCruz reagent for Gel Supershift and ChIP applications, sc-25742 X, 200 µg/0.1 ml
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
NCoA-3 Background Information
Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone-responsive elements. This family includes GRIP1 (for GR interacting protein 1), also designated NCoA-2 or TIF-2; SRC-1 (for steroid receptor coactivator-1), also designated NCoA-1; and NCoA-3, also designated RAC3, ACTR, AIB-1 (for amplified in breast cancer) and p/CIP (for p300/CBP/co-integrator protein), which displays elevated expression in estrogen receptor positive ovarian and breast cancers and is required for the transcriptional activation of p300/CBP-dependent transcription factors.
| NCoA-3 (H-80) Product Citations |
See how others have used NCoA-3 (H-80): sc-25742 antibody and or NCoA-3 (H-80) antibody conjugates.
5 total citations Loading citations.
|
| |
|
|
|
NCoA-3 (H-80)
Click on image to enlarge
|
|
NCoA-3 (H-80): sc-25742. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing nuclear and cytoplasmic localization.
NCoA-3 (H-80): sc-25742. Immunoperoxidase staining of formalin fixed, paraffin-embedded human esophagus tissue showing nuclear staining of surface epithelial cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
NCoA-3 (H-80): sc-25742. Western blot analysis of NCoA-3 expression in HeLa whole cell lysate.
NCoA-3 (H-80): sc-25742. Western blot analysis of NCoA-3 expression in K-562 whole cell lysate.
NCoA-3 (H-80): sc-25742. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing nuclear staining of urothelial cells.
|
|
Download
|
|
