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HGK Antibody (M-190): sc-25738

 |  Datasheet

(Based on data analysis)

  • HGK Antibody (M-190) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 511-700 of HGK of mouse origin
  • recommended for detection of HGK of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • See 1 citations for HGK Antibody (M-190)
 
Full-length HGK protein sequence with immunogen highlighted:
MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTVTAAIKVMDVTEDEEEEITLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGGPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLHDHRRPHAQQQPPPPQQQDRSKPSFHAPEPKPHYDPADRAREVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEGLSQSSDSKSEVPEPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGGGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSPRQESAAKKPDDKKEVFRSLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSPNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELLHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCGRNDKVFFSSVRSGGSSQVYFMTLGRTSLLSW

See additional HGK Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
HGK Antibody (M-190) sc-25738 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HGK siRNA (h) sc-39243 10 µM $258
HGK siRNA (m) sc-39244 10 µM $258
HGK (h)-PR sc-39243-PR 10 µM, 20 µl $23
HGK (m)-PR sc-39244-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HGK shRNA Plasmid (h) sc-39243-SH 20 µg $520
HGK shRNA Plasmid (m) sc-39244-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HGK shRNA (h) Lentiviral Particles sc-39243-V 200 µl $625
HGK shRNA (m) Lentiviral Particles sc-39244-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MDA-MB-468 Cell Lysate sc-2282 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MAP4K4 9448 2q11.2 NM_004834, NM_145686, NM_145687 O95819
604666
Mouse Map4k4 26921 1 B P97820
N/A
 


HGK (HPK/GC kinase-like kinase), also known as mitogen-activated protein kinase kinase kinase kinase 4, MAPK/ERK kinase kinase kinase 4, MEKKK 4 or NCK-interacting kinase (NIK), is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase, Ste20. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase and HGK. HGK, like many of the Ste20-like kinases, has been shown to activate the SAPK/JNK stress response pathway. HGK interacts with MEK kinase-1 and is thought to act upstream of MEK kinase-1 in the SAPK/JNK signaling pathway. Both the kinase domain and the C-terminal regulatory domain of HGK are required for full activation.

HGK Antibody (M-190) Product Citations
See how others have used HGK Antibody (M-190) and or HGK Antibody (M-190) conjugates.


1 total citations
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HGK Antibody (M-190) Data
Click on image to enlarge
HGK (M-190): sc-25738. Western blot analysis of HGK expression in rat brain tissue extract.
HGK (M-190): sc-25738. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.
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