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MCH-1R Antibody (H-190): sc-25667

 |  Datasheet

(Based on data analysis)

  • MCH-1R Antibody (H-190) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1-190 of MCH-1R of human origin
  • recommended for detection of MCH-1R of mouse, rat and human origin by WB, IP, IF and ELISA
 

See additional MCH Antibodies including MCH-2R, MCH-1R, MCH and pro-MCH.

Also see chemical MCH-1R Inhibitors for functional analysis of cellular responses to MCH-1R.


Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R Antibody (H-190) sc-25667 200 µg/ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R CRISPR/Cas9 KO Plasmid (m) sc-431527 20 µg $345
MCH-1R HDR Plasmid (m) sc-431527-HDR 20 µg $385
MCH-1R CRISPR/Cas9 KO Plasmid (h) sc-402512 20 µg $345
MCH-1R HDR Plasmid (h) sc-402512-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R siRNA (h) sc-42017 10 µM $258
MCH-1R siRNA (m) sc-42018 10 µM $258
MCH-1R (h)-PR sc-42017-PR 10 µM, 20 µl $23
MCH-1R (m)-PR sc-42018-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R shRNA Plasmid (h) sc-42017-SH 20 µg $520
MCH-1R shRNA Plasmid (m) sc-42018-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R shRNA (h) Lentiviral Particles sc-42017-V 200 µl $625
MCH-1R shRNA (m) Lentiviral Particles sc-42018-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
rat cerebellum extract sc-2398 500 µg/200 µl $104
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MCHR1 2847 22q13.2 NM_005297 Q99705
601751
Mouse Mchr1 207911 15 E1 Q8JZL2
N/A
 


Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide, which is mainly expressed in the hypothalamus (1-2). MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH) (1-4). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor (5). MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus (1,2,6). MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity (7).