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Epac Antibody (H-70): sc-25632

 |  Datasheet

(Based on data analysis)

  • Epac Antibody (H-70) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 43-112 mapping at the N-terminus of Epac of human origin
  • recommended for detection of Epac of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
  • agarose conjugate for IP studies, sc-25632 AC, 500 µg/0.25 ml agarose
  • See 7 citations for Epac Antibody (H-70)
 
Full-length Epac protein sequence with immunogen highlighted:
MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPVRTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP

See additional Epac Antibodies including Epac and Epac2.

Also see chemical Epac Activators for functional analysis of cellular responses to Epac.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Epac Antibody (H-70) sc-25632 200 µg/ml $279
Epac Antibody (H-70) AC sc-25632 AC 500 µg/ml, 25% ag $366
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Epac CRISPR/Cas9 KO Plasmid (h) sc-401807 20 µg $345
Epac HDR Plasmid (h) sc-401807-HDR 20 µg $385
Epac2 CRISPR/Cas9 KO Plasmid (h) sc-402096 20 µg $345
Epac2 HDR Plasmid (h) sc-402096-HDR 20 µg $385
Epac CRISPR/Cas9 KO Plasmid (m) sc-432410 20 µg $345
Epac HDR Plasmid (m) sc-432410-HDR 20 µg $385
Epac2 CRISPR/Cas9 KO Plasmid (m) sc-425208 20 µg $345
Epac2 HDR Plasmid (m) sc-425208-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Epac siRNA (h) sc-41700 10 µM $258
Epac siRNA (m) sc-41701 10 µM $258
Epac siRNA (r) sc-270246 10 µM $258
Epac (h)-PR sc-41700-PR 10 µM, 20 µl $23
Epac (m)-PR sc-41701-PR 10 µM, 20 µl $23
Epac (r)-PR sc-270246-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Epac shRNA Plasmid (h) sc-41700-SH 20 µg $520
Epac shRNA Plasmid (m) sc-41701-SH 20 µg $520
Epac shRNA Plasmid (r) sc-270246-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Epac shRNA (h) Lentiviral Particles sc-41700-V 200 µl $625
Epac shRNA (m) Lentiviral Particles sc-41701-V 200 µl $625
Epac shRNA (r) Lentiviral Particles sc-270246-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104
Epac (h): 293T Lysate sc-111627 100 µg/200 µl $205
Epac (h2): 293T Lysate sc-113416 100 µg/200 µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Epac (h4): 293T Lysate sc-170772 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RAPGEF3 10411 12q13.11 NM_006105 O95398
606057
Mouse Rapgef3 223864 15 F1 Q8VCC8
N/A
 


3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac (Epac1, cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the Ras family GTPases Rap 1 and Rap 2 by promoting GTP binding in a cAMP-dependent manner. Eukaryotic cAMP is a second messenger that induces physiological responses such as gene expression, growth, differentiation, secretion and neurotransmission. The human Epac gene maps to chromosome 12q13.11 with transcript being abundant in the kidney and heart. In situ hybridization indicates expression of Epac in adult rat brain and selective expression in neonatal brain, including septum and thalamus.

Epac Antibody (H-70) Product Citations
See how others have used Epac Antibody (H-70) and or Epac Antibody (H-70) conjugates.


7 total citations
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Epac Antibody (H-70) Data
Click on image to enlarge
Epac (H-70): sc-25632. Western blot analysis of Epac expression in non-transfected: sc-117752 (A) and human Epac transfected: sc-113416 (B) 293T whole cell lysates.
Epac (H-70): sc-25632. Western blot analysis of Epac expression in non-transfected: sc-117752 (A) and human Epac transfected: sc-111627 (B) 293T whole cell lysates.
Epac (H-70): sc-25632. Western blot analysis of Epac expression in non-transfected: sc-117752 (A) and human Epac transfected: sc-170772 (B) 293T whole cell lysates.
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