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Salinomycin (CAS 53003-10-4)

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Application:A polyether potassium ionophore
CAS Number:53003-10-4
Molecular Weight:751.00
Molecular Formula:C42H70O11
Refer to Certificate of Analysis for lot specific data (including water content).
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Salinomycin sc-253530 5 mg $150
Salinomycin sc-253530A 25 mg $510
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Salinomycin is a polyether potassium ionophore antibiotic, which promotes cation movement across biological membranes via exchange-diffusion. As a result of this cation exchange, the transmembrane gradients are altered, which leads to changes in cellular function and metabolism. In addition, Salinomycin acts as a chelating agent towards monovalent cations such as sodium and potassium ions. Alternate studies suggest that Salinomycin selectively inhibits cancer stem-like cells.
Technical Information
Physical State:Solid
Derived from:Streptomyces sp.
Solubility:Solubility: Soluble in methanol (10 mg/mL)
Storage:Store at -20° C
Melting Point:112.5-113.5 lit
Boiling Point:~839.2° C at 760 mmHg (Predicted)
Density:~1.2 g/cm3 (Predicted)
Safety and Reference Information
Transport:UN 3462, Class 6.1, Packing group II
PubChem CID:72370
MDL Number:MFCD00865281
EC Number:258-290-1
SMILES:CC[C@H]([C@@H]1[C@H](C[C@H]([C@@]2(O1)C=C[C@H]([C@]3(O2)CC[C@@](O3)(C)[C@H]4 CC[C@@]([C@@H](O4)C)(CC)O)O)C)C)C(=O)[C@@H](C)[C@H]([C@H](C)[C@H]5[C@H](CCC( O5)[C@@H](CC)C(=O)O)C)O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Salinomycin Product Reviews

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1. Dong, T.T., et al. 2011. Ann Surg Oncol. [Epub ahead of print]. PMID: 21267784
2. Wang, Y. 2011. Med Chem. [Epub ahead of print]. PMID: 21222617
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