Date published: 2025-10-27

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Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) (CAS 1405-97-6)

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Application:
CAS Number:
1405-97-6
Molecular Weight:
1882.3
Molecular Formula:
C99H140N20O17
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is a linear polypeptide antibiotic with a mixture of gramicidin A, B, C, and D. Gramicidin D is a channel-forming ionophore that flip-flops slowly across the membrane and is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers. Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is active against the Gram-positive bacterium S. aureus but not Gram-negative E. coli. It inhibits growth of bacteria by forming pores and channels in the cell wall, which increases its permeability to monovalent cations.


Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) (CAS 1405-97-6) References

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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis), 100 mg

sc-252865
100 mg
$27.00

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis), 500 mg

sc-252865A
500 mg
$71.00