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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within an internal region of CD53 of mouse origin
- recommended for detection of CD53 of mouse and rat origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
- blocking peptide, sc-25214 P
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Ordering Information
Recommended Support Products:
(click button of application of choice)
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Mouse |
Cd53 |
12508 |
3 F2.3 |
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Q61451
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N/A |
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CD53 Background Information
The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. The tetraspanin superfamily (CD9, CD37, CD53, CD63, CD81 and CD82) comprises a group of cell-surface proteins that are involved in cell activation and signal transduction as well as in cell adhesion, motility and metastasis. Tetraspanin transmembrane proteins have a metastasis suppressor effect by acting as cell motility brakes in tumor cells. Human neutrophils express high levels of CD53, an N-glycosylated pan-leukocyte antigen and the true homolog of the rat MRC-OX-44 antigen. CD53 is expressed on B cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T cells. |
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CD53 (M-15)
Click on image to enlarge
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CD53 (M-15): sc-25214. Western blot analysis of CD53 expression in WEHI-231 (A), MCP-5 (B) and WR19L (C) whole cell lysates.
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