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Thrombospondin 5 Antibody (E-20): sc-25163

 |  Datasheet

(Based on data analysis)
  • Thrombospondin 5 Antibody (E-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of mature Thrombospondin 5 (also designated COMP) of human origin
  • recommended for detection of precursor and mature Thrombospondin 5 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-25163 P
 

See additional Thrombospondin Antibodies including Thrombospondin, Thrombospondin 1, Thrombospondin 2, Thrombospondin 3, Thrombospondin 4 and Thrombospondin 5.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Thrombospondin 5 Antibody (E-20) sc-25163 200 µg/ml $279
Thrombospondin 5 (E-20) P sc-25163 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Thrombospondin 5 siRNA (h) sc-43195 10 µM $258
Thrombospondin 5 siRNA (m) sc-43196 10 µM $258
Thrombospondin 5 (h)-PR sc-43195-PR 10 µM, 20 µl $23
Thrombospondin 5 (m)-PR sc-43196-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Thrombospondin 5 shRNA Plasmid (h) sc-43195-SH 20 µg $520
Thrombospondin 5 shRNA Plasmid (m) sc-43196-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Thrombospondin 5 shRNA (h) Lentiviral Particles sc-43195-V 200 µl $625
Thrombospondin 5 shRNA (m) Lentiviral Particles sc-43196-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Thrombospondin 5 (h2): 293T Lysate sc-115080 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human COMP 1311 19p13.11 NM_000095 P49747
 600310
Mouse Comp 12845 8 B3.3 Q9R0G6
 N/A
 

Thrombospondin 5 (also designated THBS5, cartilage oligomeric matrix protein or COMP) is the fifth member of the Thrombospondin family of extracellular matrix proteins. The Thrombospondin family share overall homology, with significant homology in their carboxy-terminal globular domains. They all contain type 2 (epidermal growth factor-like) and type 3 (calmodulin-like) repeats in their central domains. The human COMP/THBS5 gene maps to chromosome 19p13.1. Thrombospondin 5 is expressed in all types of cartilage, tendon and vascular smooth muscle. Its localization in cartilage is developmentally regulated to the chondrocyte territorial and interterritorial matrix. Thrombospondin 5 also binds to Collagen Type I, II and IX in a zinc-dependent manner. Mutations in the COMP/THBS5 gene are associated with the human genetic disorders pseudoachondroplasia (PSACH) and some types of multiple epiphyseal dysplasia (MED). PSACH and MED are autosomal dominant chondrodysplasias, which cause mild to severe short-limb dwarfism and early-onset osteoarthritis.