Date published: 2026-8-19

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(Triphenylphosphoranylidene)acetonitrile (CAS 16640-68-9)

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CAS Number:
16640-68-9
Molecular Weight:
301.32
Molecular Formula:
C20H16NP
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Wittig reagent for preparing α,, unsaturated nitriles from carbonyl compounds.(1)


(Triphenylphosphoranylidene)acetonitrile (CAS 16640-68-9) References

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  2. Preparation and chemistry of phosphoranyl-derived iodanes.  |  Zhdankin, VV., et al. 2003. J Org Chem. 68: 1018-23. PMID: 12558430
  3. A highly regio- and stereoselective formation of bicyclo[4.2.0]oct-5-ene derivatives through thermal intramolecular [2 + 2] cycloaddition of allenes.  |  Ohno, H., et al. 2007. J Org Chem. 72: 4378-89. PMID: 17489635
  4. Toward the Total Synthesis of Scleritodermin A: Preparation of the C(1)-N(15) Fragment.  |  Sellanes, D., et al. 2007. Tetrahedron Lett. 48: 1827-1830. PMID: 18320006
  5. Synthesis of 9-fluorenylidenes and 9,10-phenanthrenes through palladium-catalyzed aryne annulation by o-halostyrenes and o-halo allylic benzenes.  |  Worlikar, SA. and Larock, RC. 2009. J Org Chem. 74: 9132-9. PMID: 19902957
  6. Improved synthesis of (3E,6Z,9Z)-1,3,6,9-nonadecatetraene, attraction inhibitor of bruce spanworm, Operophtera bruceata, to pheromone traps for monitoring winter moth, Operophtera brumata.  |  Khrimian, A., et al. 2010. J Agric Food Chem. 58: 1828-33. PMID: 20041659
  7. Efficient access to peptidyl ketones and peptidyl diketones via C-alkylations and C-acylations of polymer-supported phosphorus ylides followed by hydrolytic and/or oxidative cleavage.  |  El-Dahshan, A., et al. 2010. Biopolymers. 94: 220-8. PMID: 20225299
  8. Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.  |  Cinelli, MA., et al. 2015. J Med Chem. 58: 8694-712. PMID: 26469213
  9. A sandwich-type cluster containing Ge@Pd3 planar fragment flanked by aromatic nonagermanide caps.  |  Xu, HL., et al. 2020. Nat Commun. 11: 5286. PMID: 33082326
  10. Ruthenium(ii)-catalyzed regioselective direct C4- and C5-diamidation of indoles and mechanistic studies.  |  Devkota, S., et al. 2021. Chem Sci. 12: 11427-11437. PMID: 34567497
  11. Reactions of phosphorus compounds. VII. Carbanion stabilization and resulting effects on P-ylid reactivity  |  Speziale, A. J., & Ratts, K. W. 1963. Journal of the American Chemical Society. 85(18): 2790-2795.
  12. Negatively substituted acetylenes. III. Reverse Wittig reactions with triphenylphosphine oxide and triphenylarsine oxide.  |  Ciganek, E. 1970. The Journal of Organic Chemistry. 35(6): 1725-1729.
  13. Stereocontrolled transformation of cyclohexene β-amino esters into syn-or anti-difunctionalized acyclic β2, 3-amino acid derivatives  |  Cherepanova, M., Kiss, L., & Fülöp, F. 2014. Tetrahedron. 70(15): 2515-2522.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(Triphenylphosphoranylidene)acetonitrile, 5 g

sc-251386
5 g
$110.00