Date published: 2026-1-6

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Propyl gallate (CAS 121-79-9)

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Alternate Names:
Propyl 3,4,5-trihydroxybenzoate
Application:
Propyl gallate is a biochemical used as an anti-fade reagent in fluorescence microscopy
CAS Number:
121-79-9
Purity:
≥98%
Molecular Weight:
212.20
Molecular Formula:
C10H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propyl gallate functions as an antioxidant in experimental applications. It acts by inhibiting the oxidation of other molecules, thereby preventing the formation of free radicals and the degradation of certain substances. At the molecular level, propyl gallate works by donating hydrogen atoms to free radicals, stabilizing them and preventing further damage to the experimental system. Propyl Gallate′s mechanism of action involves interrupting the chain reaction of oxidation, which can be beneficial in maintaining the stability of certain experimental samples. By effectively scavenging free radicals, propyl gallate plays a role in protecting the integrity of experimental materials and preventing unwanted chemical reactions.


Propyl gallate (CAS 121-79-9) References

  1. Propyl gallate inhibits TPA-induced inflammation via the nuclear factor-κB pathway in human THP-1 monocytes.  |  Hsu, HC., et al. 2013. Exp Ther Med. 5: 964-968. PMID: 23408313
  2. Propyl gallate sensitizes human lung cancer cells to cisplatin-induced apoptosis by targeting heme oxygenase-1 for TRC8-mediated degradation.  |  Jo, EJ., et al. 2016. Eur J Pharmacol. 788: 321-327. PMID: 27375080
  3. Propyl gallate/cyclodextrin supramolecular complexes with enhanced solubility and radical scavenging capacity.  |  Li, Q., et al. 2018. Food Chem. 245: 1062-1069. PMID: 29287323
  4. Propyl gallate inhibits hepatocellular carcinoma cell growth through the induction of ROS and the activation of autophagy.  |  Wei, PL., et al. 2019. PLoS One. 14: e0210513. PMID: 30653551
  5. Safety and efficacy of propyl gallate for all animal species.  |  , ., et al. 2020. EFSA J. 18: e06069. PMID: 32874281
  6. Propyl gallate reduces the growth of lung cancer cells through caspase‑dependent apoptosis and G1 phase arrest of the cell cycle.  |  Park, WH. 2020. Oncol Rep. 44: 2783-2791. PMID: 33125113
  7. Propyl gallate decreases the proliferation of Calu-6 and A549 lung cancer cells via affecting reactive oxygen species and glutathione levels.  |  Park, WH. 2022. J Appl Toxicol. 42: 436-449. PMID: 34464457
  8. Gallic Acid Derivatives Propyl Gallate and Epigallocatechin Gallate Reduce rRNA Transcription via Induction of KDM2A Activation.  |  Tanaka, Y. and Tsuneoka, M. 2021. Biomolecules. 12: PMID: 35053178
  9. Propyl Gallate Treatment Improves the Postharvest Quality of Winter Jujube (Zizyphus jujuba Mill. cv. Dongzao) by Regulating Antioxidant Metabolism and Maintaining the Structure of Peel.  |  Wang, C., et al. 2022. Foods. 11: PMID: 35053969
  10. Cu3(PO4)2/BiVO4 photoelectrochemical sensor for sensitive and selective determination of synthetic antioxidant propyl gallate.  |  Ye, C., et al. 2022. Anal Bioanal Chem. 414: 4139-4147. PMID: 35441261
  11. A pharmacodynamic investigation to assess the synergism of orbifloxacin and propyl gallate against Escherichia coli.  |  Abbas, MA., et al. 2022. Front Pharmacol. 13: 989395. PMID: 36188537
  12. Pharmacokinetic and toxicological overview of propyl gallate food additive.  |  Javaheri-Ghezeldizaj, F., et al. 2023. Food Chem. 423: 135219. PMID: 37178593
  13. Propyl gallate as a hepatoprotector in vitro and in vivo.  |  Wu, TW., et al. 1994. Biochem Pharmacol. 48: 419-22. PMID: 8053938

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propyl gallate, 100 g

sc-250794
100 g
$77.00

Propyl gallate, 250 g

sc-250794A
250 g
$224.00

Propyl gallate, 500 g

sc-250794B
500 g
$285.00

Propyl gallate, 1 kg

sc-250794C
1 kg
$510.00

Propyl gallate, 2 kg

sc-250794D
2 kg
$816.00

Propyl gallate, 5 kg

sc-250794E
5 kg
$1632.00