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TPST-2 Antibody (C-20): sc-25036

 |  Datasheet

(Based on data analysis)

  • TPST-2 Antibody (C-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of TPST-2 of human origin
  • recommended for detection of TPST-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • blocking peptide, sc-25036 P
 

See additional TPST Antibodies including TPST-2, TPST-1 and TPST.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
TPST-2 Antibody (C-20) sc-25036 200 µg/ml $279
TPST-2 (C-20) P sc-25036 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TPST-2 siRNA (h) sc-41077 10 µM $258
TPST-2 siRNA (m) sc-41078 10 µM $258
TPST-2 (h)-PR sc-41077-PR 10 µM, 20 µl $23
TPST-2 (m)-PR sc-41078-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TPST-2 shRNA Plasmid (h) sc-41077-SH 20 µg $520
TPST-2 shRNA Plasmid (m) sc-41078-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TPST-2 shRNA (h) Lentiviral Particles sc-41077-V 200 µl $625
TPST-2 shRNA (m) Lentiviral Particles sc-41078-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TPST-2 (m): 293T Lysate sc-124239 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TPST2 8459 22q12.1 NM_001008566, NM_003595 O60704
 603126
Mouse Tpst2 22022 5 F O88856
 N/A
 

The tyrosylprotein sulfotransferases TPST-1 and TPST-2 catalyze the sulfation of tyrosine residues within secreted and membrane-bound proteins, such as cell adhesion molecules, G protein-coupled receptors, coagulation factors, serpins, extracellular matrix proteins and hormones. Although both TPST-1 and TPST-2 utilize 3'-phosphoadenosine 5'-phosphosulfate as their sulfate donor, they differ in their substrate specificity. The TPSTs are evolutionarily conserved proteins found in a wide variety of species, including human, mouse, C. elegans, and plants. They are ubiquitously expressed in several tissues, including liver, lung, heart and cerebellum. Both TPST-1 and TPST-2 localize to the Golgi complex. Chronic alcohol consumption stimulates a threefold increase in TPST levels in the gastric mucosa and liver, indicating that TPST may play a role in alcoholism. The genes encoding human TPST-1 and TPST-2 map to chromosomes 7q11.21 and 22q12.1, respectively.
TPST-2 Antibody (C-20) Data
Click on image to enlarge
sc-25036
TPST-2 (C-20): sc-25036. Western blot analysis of TPST-2 expression in non-transfected: sc-117752 (A) and mouse TPST-2 transfected: sc-124239 (B) 293T whole cell lysates.
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