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MFSD6L Antibody (D-16): sc-243477

 |  Datasheet

(Based on data analysis)

  • MFSD6L Antibody (D-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of MFSD6L of human origin
  • recommended for detection of MFSD6L of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with MFSD6; also reactive with additional species, including canine and porcine
  • blocking peptide, sc-243477 P
 

See additional MFSD6 Antibodies including MFSD6 and MFSD6L.

Ordering InformationGene Info
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
MFSD6L Antibody (D-16) sc-243477 200 µg/ml $279
MFSD6L (D-16) P sc-243477 P
(peptide)
100 µg/0.5 ml $61
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MFSD6L 162387 17p13.1 NM_152599 Q8IWD5
n/a
Mouse Mfsd6l 215723 11 B3 NM_146004 Q8R3N2
N/A
 


MFSD6L (major facilitator superfamily domain containing 6-like), also known as FP7072, is a 586 amino acid multi-pass membrane protein of the MFSD6 family and major facilitator superfamily. The gene encoding MFSD6L maps to human chromosome 17, which contains about 81 million bases and 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though it is specifically recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth.