Pol III RPC39 Background Information Eukaryotes produce three distinct classes of RNA polymerase, Pol I, II and III. Each polymerase is responsible for the synthesis of a different class of RNA. RNA polymerase I (Pol I) transcribes the rRNA (ribosomal RNA) genes for the precursor of the 28S, 18S and 5.8S molecules of the ribosome. RNA polymerase II transcribes protein-encoding genes into mRNA (messenger RNA) and snRNA (small nuclear RNA) genes into snRNAs that influence the processing of other classes of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes.
Pol III RPC39 (C39-2)
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Pol III (C39-2): sc-23913. Western blot analysis of Pol III expression in HeLa (A) and A-431 (B) nuclear extracts.
Pol III RPC39 siRNA (h): sc-36292. Western blot analysis of Pol III RPC39 expression in non-transfected control (A) and Pol III RPC39 siRNA transfected (B) HeLa cells. Blot probed with Pol III RPC39 (C39-2): sc-23913. GAPDH (FL-335): sc-25778 used as specificity and loading control.