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cyclin A (BF683) Antibody: sc-239 |
| Datasheet |
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- mouse monoclonal IgE, 200 µg/ml
- raised against recombinant full length cyclin A of human origin
- recommended for detection of cyclin A of human origin by WB, IP, KA, IF, FCM and ELISA
- agarose conjugate for IP studies, sc-239 AC, 500 µg/0.25 ml agarose
- TransCruz Gel Supershift reagent for ChIP assay or gel supershift of cyclin A/E2F oligonucleotide complexes, sc-239 X, 200 µg/0.1 ml
- phycoerythrin conjugate for intracellular FCM, sc-239 PE, 100 tests
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
CCNA2 |
890 |
4q27 |
NM_001237 |
P20248
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123835 |
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cyclin A Background Information
The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin- dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.
| cyclin A (BF683) Product Citations |
See how others have used cyclin A (BF683): sc-239 antibody and or cyclin A (BF683) antibody conjugates.
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cyclin A (BF683)
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cyclin A (BF683): sc-239. Western blot analysis of cyclin A p60 expression in K-562 human whole cell lysate.
cyclin A (BF683) PE: sc-239 PE. Intracellular FCM analysis of fixed and permeabilized K-562 cells. Black line histogram represents the isotype control, normal mouse IgE.
cyclin A (BF683): sc-239. Western blot analysis of cyclin A expression in untreated (A) and Flurbiprofen ( sc-202158) treated (B) Caco-2 whole cell lysates. Note down regulation of cyclin A expression in lane B. cyclin A (BF683): sc-239. Western blot analysis of cyclin A expression in K-562 (A) and HuT 78 (B) whole cell lysates.
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