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home » Lymphocyte Signaling » NKG2 Antibody / NKG2 Antibodies » NKG2-D (C7): sc-23890

NKG2-D (C7) Antibody: sc-23890

  |  Datasheet
  • Armenian hamster monoclonal IgG, 200 µg/ml
  • raised against ectodomain of recombinant NKG2D of mouse origin
  • recommended for detection of NKG2-D of mouse origin by FCM
  • also provided azide-free for blocking the receptor, sc-23890 L, 200 µg/0.1 ml
 
Additional NKG2 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Klrk1 27007 6 F3 O54709
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D (C7) sc-23890 200 µg/ml $279
NKG2-D (C7) L sc-23890 L 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D siRNA (m) sc-42949 10 µM $258
NKG2-D (m)-PR sc-42949-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D shRNA Plasmid (m) sc-42949-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D shRNA (m) Lentiviral Particles sc-42949-V 200 µl $625

NKG2-D Background Information
The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired Immunoglobulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, ©∂ T cells, and CD8+ å∫ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
NKG2-D (C7)
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sc-23890
NKG2-D (C7) PE: sc-23890 PE. FCM analysis of NKG2-D transfected CHO cells. Black line histogram represents the isotype control, normal Armenian hamster IgG: sc-2875.
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