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home » Lymphocyte Signaling » NKG2 Antibody / NKG2 Antibodies » NKG2-D (1D11): sc-23869

NKG2-D (1D11) Antibody: sc-23869

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • recommended for detection of NKG2-D of human origin by WB and FCM
  • fluorescein (sc-23869 FITC), phycoerythrin (sc-23869 PE), PerCP (sc-23869 PerCP) and PerCP-Cy5.5 (sc-23869 PCPC5) conjugates for FCM, 100 tests
  • also provided azide free for blocking the binding of MICA with NKG2-D, sc-23869 L, 200 µg/0.1 ml
  • Alexa Fluor® 488 (sc-23869 AF488) and Alexa Fluor® 647 (sc-23869 AF647) conjugates for FCM; 100 µg/2 ml
 
Additional NKG2 Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human KLRK1 22914 12p13.2 NM_007360 P26718
 n/a
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D (1D11) sc-23869 200 µg/ml $279
NKG2-D (1D11) Alexa Fluor® 488 sc-23869 AF488 100 µg/2 ml $314
NKG2-D (1D11) Alexa Fluor® 647 sc-23869 AF647 100 µg/2 ml $314
NKG2-D (1D11) FITC sc-23869 FITC 100 tests in 2 ml $292
NKG2-D (1D11) L sc-23869 L 200 µg/0.1 ml $279
NKG2-D (1D11) PCPC5 sc-23869 PCPC5 100 tests in 2ml $310
NKG2-D (1D11) PE sc-23869 PE 100 tests in 2ml $303
NKG2-D (1D11) PerCP sc-23869 PerCP 100 tests in 2ml $310
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D siRNA (h) sc-42948 10 µM $258
NKG2-D (h)-PR sc-42948-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D shRNA Plasmid (h) sc-42948-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NKG2-D shRNA (h) Lentiviral Particles sc-42948-V 200 µl $625

NKG2-D Background Information
The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired Immunoglobulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, ©∂ T cells, and CD8+ å∫ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.

NKG2-D (1D11) Product Citations
See how others have used NKG2-D (1D11): sc-23869 antibody and or NKG2-D (1D11) antibody conjugates.


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NKG2-D (1D11)
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sc-23869
NKG2-D (1D11) PE: sc-23869 PE. FCM analysis of TCR α/β+, CD8+ human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1: sc-2866.
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