santa cruz biotechnology, inc.
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- mouse monoclonal IgG2a; 200 µg/ml
- raised against mouse LTK-MICA transfectants
- recommended for detection of MICA and MICB of human origin by IP and FCM
- fluorescein (sc-23868 FITC) and phycoerythrin (sc-23868 PE) conjugates for FCM, 100 tests
- also provided azide free for inhibiting TCR-mediated cytotoxicity, sc-23868 L, 200 µg/0.1 ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
MICA |
4276 |
6p21.33 |
NM_000247 |
Q29983
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MICA/B Background Information
MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with ∫-2-Microglobulin. The expression is induced on proliferating or heat shock-stressed epithelial cells. MICA and MICB are broadly recognized by intestinal epithelial V∂1 ©∂ T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.
| MICA/B (6D4) Product Citations |
See how others have used MICA/B (6D4): sc-23868 antibody and or MICA/B (6D4) antibody conjugates.
2 total citations Loading citations.
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MICA/B (6D4)
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MICA/B (6D4): sc-23868. FCM analysis of MCF7 cells. Black line histogram represents the isotype control, normal mouse IgG 2a: sc-2866. |
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