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home » Transcription Regulators » NAB Antibody / NAB Antibodies » NAB2 (1C4): sc-23867

NAB2 (1C4) Antibody: sc-23867

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against recombinant human NAB2 protein
  • recommended for detection of NAB2 of human origin by WB, IP, IF and IHC(P)
 
Additional NAB Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NAB2 4665 12q13.3 NM_005967 Q15742
 n/a
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 (1C4) sc-23867 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 siRNA (h) sc-36014 10 µM $258
NAB2 (h)-PR sc-36014-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 shRNA Plasmid (h) sc-36014-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 shRNA (h) Lentiviral Particles sc-36014-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 + PMA nuclear extract sc-2131 1000 µg $143
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
NAB2 (h): 293T Lysate sc-117107 100µg/200µl $205

NAB2 Background Information
Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.

NAB2 (1C4) Product Citations
See how others have used NAB2 (1C4): sc-23867 antibody and or NAB2 (1C4) antibody conjugates.


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NAB2 (1C4)
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sc-23867
NAB2 (1C4): sc-23867. Western blot analysis of NAB2 expression in PMA-treated K-562 nuclear extract.
sc-23867
NAB2 (1C4): sc-23867. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human ovary tumor showing nuclear localization.
sc-23867
NAB2 (1C4): sc-23867. Western blot analysis of NAB2 expression in non-transfected 293T: sc-117752 (A), human NAB2 transfected 293T: sc-117107 (B) and K-562 (C) whole cell lysates.
sc-23867
NAB2 (1C4): sc-23867. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
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