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- rabbit polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of TFIIE-β of human origin
- recommended for detection of TFIIE-β p34 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-238 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-238 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
GTF2E2 |
2961 |
8p12 |
NM_002095 |
P29084
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189964 |
| Mouse |
Gtf2e2 |
68153 |
8 A4 |
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Q9D902
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N/A |
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TFIIE-β Background Information
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Human TFIIE consists of two subunits, å and ∫. The structure of TFIIE appears to be a heterotetramer (å2∫2); both subunits are required for optimal basal-level transcription.
| TFIIE-β (C-21) Product Citations |
See how others have used TFIIE-β (C-21): sc-238 antibody and or TFIIE-β (C-21) antibody conjugates.
5 total citations Loading citations.
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TFIIE-β (C-21)
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Western blot analysis of TFIIE-β p34 expression in HeLa whole cell lysates (A,B). Antibodies tested include TFIIE-β (C-21): sc-238 (A) and TFIIE-β (H-291): sc-6935 (B). Western blot analysis of TFIIE-β recombinant protein tested at 10 ng using TFIIE-β (C-21): sc-238 at a dilution of 1:10,000.
TFIIE β (C-21): sc-238. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urothelial cancer tissue showing nuclear and cytoplasmic staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
TFIIE-β (C-21): sc-238. Immunofluorescence staining of normal mouse lymph node frozen section showing cytoplasmic and nuclear staining.
TFIIE-β (C-21): sc-238. Western blot analysis of TFIIE-β expression in non-transfected 293T: sc-117752 (A), mouse TFIIE-β transfected 293T: sc-124003 (B) and HL-60 (C) whole cell lysates. |
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