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p-c-Kit Antibody (Tyr 721)-R: sc-23766-R

 |  Datasheet

(Based on data analysis)

  • p-c-Kit (Tyr 721)-R Antibody is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Tyr 721 of c-Kit of human origin
  • recommended for detection of Tyr 721 phosphorylated c-Kit of mouse, rat and human origin by WB, IF and ELISA
  • blocking peptide, sc-23766 P
 

See additional c-Kit Antibodies.

Also see c-Kit Inhibitors for functional analysis of cellular responses to c-Kit.


Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-c-Kit (Tyr 721) P sc-23766 P
(peptide)
 100 µg/0.5 ml $61
p-c-Kit (Tyr 721)-R Antibody sc-23766-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Kit siRNA (h) sc-29225 10 µM $258
c-Kit siRNA (m) sc-29852 10 µM $258
c-Kit (h)-PR sc-29225-PR 10 µM, 20 µl $23
c-Kit (m)-PR sc-29852-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Kit shRNA Plasmid (h) sc-29225-SH 20 µg $520
c-Kit shRNA Plasmid (m) sc-29852-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Kit shRNA (h) Lentiviral Particles sc-29225-V 200 µl $625
c-Kit shRNA (m) Lentiviral Particles sc-29852-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
A-431 + EGF Whole Cell Lysate sc-2202 500 µg/200 µl $104

The c-Kit proto-oncogene has been identified as a member of the receptor tyrosine kinase family and more specifically has been shown to be closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene, v-Kit, encodes a transmembrane receptor. c-Kit has also been show to be identical with the product of the W locus in mice and as such is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and shown to be encoded at the murine steel (SI) locus. Two sites on c-Kit are able to bind SH2(CHK), the Tyr 568/570 diphosphorylated sequence and the monophosphorylated Tyr 721 sequence. SH2(CHK) binds to the two sites directly and only the Tyr 568/570, and not the Tyr 721, is able to bind SH2(CHK). The Tyr 568 and Tyr 570 residues are phosphorylated in vivo following ligand-stimulation.

p-c-Kit Antibody (Tyr 721)-R Data
Click on image to enlarge
sc-23766-R
p-c-Kit (Tyr 721)-R: sc-23766-R. Western blot analysis of c-Kit phosphorylation in untreated (A), EGF treated (B) and EGF and lambda protein phosphatase treated (C) A-431 whole cell lysates.
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