epitope mapping at the N-terminus of KIR2.4 of human origin
recommended for detection of KIR2.4 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine and bovine
KIR2.4 Background Information ATP-sensitive K+ channels play important roles in many cellular functions by coupling cell metabolism to electrical activity. The KIR (inwardly rectifying potassium channel) family of potassium channels, including the Kir2 sub-family are thought to underlie the inward rectifier current (IK1) in the heart and play an important role in the central nervous system.Inward rectifying K+ channels possess a greater tendency to allow potasium to flow into the cell rather than out of it. A fourth subunit of the Kir2 group, with somewhat different properties from the other Kir2 subunits, is designated Kir2.4. and was assigned to chromosome 19q13 and designated KCNJ14. Kir2.4 is preferentially expressed in the neural retina and are present in most retinal neurons.
KIR2.4 (L-18) Product Citations
See how others have used KIR2.4 (L-18): sc-23633 antibody and or KIR2.4 (L-18) antibody conjugates.