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home » Transcription Regulators » RUNX Antibody / RUNX Antibodies » RUNX3 (K-12): sc-23576

RUNX3 (K-12) Antibody: sc-23576

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of RUNX3 of human origin
  • recommended for detection of RUNX3 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including bovine and porcine
  • blocking peptide, sc-23576 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-23576 X, 200 µg/0.1 ml
 
Additional RUNX Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RUNX3 864 1p36.11 NM_001031680, NM_004350 Q13761
 600210
Mouse Runx3 12399 4 D3 Q64131
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
RUNX3 (K-12) sc-23576 200 µg/ml $279
RUNX3 (K-12) P sc-23576 P
(peptide)
 100 µg/0.5 ml $61
RUNX3 (K-12) X sc-23576 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RUNX3 siRNA (h) sc-37679 10 µM $258
RUNX3 siRNA (m) sc-37680 10 µM $258
RUNX3 (h)-PR sc-37679-PR 10 µM $23
RUNX3 (m)-PR sc-37680-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RUNX3 shRNA Plasmid (h) sc-37679-SH 20 µg $520
RUNX3 shRNA Plasmid (m) sc-37680-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RUNX3 shRNA (h) Lentiviral Particles sc-37679-V 200 µl $625
RUNX3 shRNA (m) Lentiviral Particles sc-37680-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104

AML-2 Background Information
The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2åB, CBFA2), RUNX2 (also designated AML-3, PEBP2åA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPåC, CBFA3), and belongs to the acute myeloid leukemia (AML) family. RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX3 is expressed in cells of hematopoietic origin, including myeloid and B-cell lines and spleen. By playing a role in controlling the growth and differentiation of gastric epithelial cells, RUNX3 is a strong candidate as a gastric cancer tumor suppressor. Specifically, hypermethylation inactivates the gene encoding RUNX3. The detection of hypermethylation at multiple regions within the RUNX3 CpG island may aid in the diagnosis and risk assessment of gastric cancer.

RUNX3 (K-12) Product Citations
See how others have used RUNX3 (K-12): sc-23576 antibody and or RUNX3 (K-12) antibody conjugates.


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