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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of TIEG2 of human origin
- recommended for detection of TIEG2 of mouse, rat and human origin by WB, IP, IF and ELISA
- blocking peptide, sc-23162 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-23162 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
KLF11 |
8462 |
2p25.1 |
NM_003597 |
O14901
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610508 |
| Mouse |
Klf11 |
194655 |
12 A1.3 |
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Q8K1S5
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N/A |
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TIEG2 Background Information
Originally isolated from osteoblastic cells, the TGF∫-inducible early gene-1 (TIEG1) is a Krupel-like zinc finger transcription factor that regulates cellular growth and differentiation. TIEG1 is regulated as an early response gene by TGF∫1. It is expressed in both acinar and ductular epithelial cells from exocrine pancreas and may serve as an early response gene in pancreatic cells, and overexpression of TIEG1 in TGF∫-sensitive epithelial cells induces apoptosis. TIEG1 is expressed at high levels in PBLs, spleen and colon, and at lower levels in thymus, small intestine, ovary, prostate and skeletal muscle. The nuclear TIEG2 protein, which shares significant homology with TIEG1, was originally isolated from globin-expressing human fetal erythroid cells. TIEG2 is expressed in fetal liver, and overexpression of TIEG2 in cultured epithelial cells inhibits cellular proliferation. TIEG2 expression is upregulated by TGF∫1 and serum deprivation.
| TIEG2 (C-12) Product Citations |
See how others have used TIEG2 (C-12): sc-23162 antibody and or TIEG2 (C-12) antibody conjugates.
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TIEG2 (C-12)
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TIEG2 (C-12): sc-23162. Western blot analysis of TIEG2 expression in Jurkat (A) and HL-60 (B) nuclear extracts.
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