Welcome to Santa Cruz Biotechnology!

ATF-6α Antibody (H-280): sc-22799

 |  Datasheet

(Based on data analysis)

  • ATF-6α Antibody (H-280) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 31-310 mapping at the N-terminus of ATF-6α of human origin
  • recommended for detection of ATF-6α of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine and canine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-22799 X, 200 µg/0.1 ml
  • agarose conjugate for IP studies, sc-22799 AC, 500 µg/0.25 ml agarose
  • See 31 citations for ATF-6α Antibody (H-280)
 
Full-length ATF-6α protein sequence with immunogen highlighted:
MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLLPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSPEPLKEDKPVTGSRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVGPANQRRHLLGFSAKEAQDTSDGIIQKNSYRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGVVEQGSNSQLMAVQYTETTSSISRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ

See additional ATF Antibodies including ATF, ATF-1, ATF-2, ATF-3, ATF-5, ATF-5 beta, ATF-6 alpha, ATF-7 and ATF-7IP.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ATF-6α Antibody (H-280) sc-22799 200 µg/ml $279
ATF-6α Antibody (H-280) AC sc-22799 AC 500 µg/ml, 25% ag $366
ATF-6α Antibody (H-280) X sc-22799 X 200 µg/0.1 ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ATF-6α CRISPR/Cas9 KO Plasmid (m) sc-432646 20 µg $345
ATF-6α HDR Plasmid (m) sc-432646-HDR 20 µg $385
ATF-6α CRISPR/Cas9 KO Plasmid (h) sc-400259 20 µg $345
ATF-6α HDR Plasmid (h) sc-400259-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ATF-6α siRNA (h) sc-37699 10 µM $258
ATF-6α siRNA (m) sc-45950 10 µM $258
ATF-6α (h)-PR sc-37699-PR 10 µM, 20 µl $23
ATF-6α (m)-PR sc-45950-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ATF-6α shRNA Plasmid (h) sc-37699-SH 20 µg $520
ATF-6α shRNA Plasmid (m) sc-45950-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ATF-6α shRNA (h) Lentiviral Particles sc-37699-V 200 µl $625
ATF-6α shRNA (m) Lentiviral Particles sc-45950-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
MCF7 nuclear extract sc-2149 250 µg/0.05 ml $143
rat liver extract sc-2395 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ATF6 22926 1q23.3 NM_007348 P18850
605537
Mouse Atf6 226641 1 H3 NP_001074773
N/A
 


ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6∫ homodimer or an ATF-6å/∫ heterodimer. Binding of the ATF-6∫ homodimer or ATF-6å/∫ heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.

ATF-6α Antibody (H-280) Product Citations
See how others have used ATF-6α Antibody (H-280) and or ATF-6α Antibody (H-280) conjugates.


31 total citations
Loading citations.
 
ATF-6α Antibody (H-280) Data
Click on image to enlarge
ATF-6α (H-280): sc-22799. Western blot analysis of ATF-6α expression in MCF7 nuclear extract.
Download