Sterigmatocystin (CAS 10048-13-2)

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Application:	A DNA synthesis inhibitor
CAS Number:	10048-13-2
Molecular Weight:	324.3
Molecular Formula:	C₁₈H₁₂O₆

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
Sterigmatocystin	sc-222329	1 mg	$39
Sterigmatocystin	sc-222329A	5 mg	$139

This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

Description

Sterigmatocystin is an inhibitor of DNA synthesis. Mycotoxin produced by strains of the common molds. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis.

Technical Information

Appearance:	Pale yellow solid.
Physical State:	Solid
Solubility:	Soluble in DMSO, ethanol, methanol or acetone
Storage:	Store at -20° C

Safety and Reference Information

Transport:	UN 3462, Class 6.1, Packing group III
PubChem CID:	5280389
SMILES:	COC1=C2C(=C3C4C=COC4OC3=C1)OC5=C(C2=O)C(=CC=C5)O

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

Effect of sterigmatocystin on rat liver nuclear RNA: W. Nel & H.E. Pretorius; Biochem. Pharmacol. 19, 957 (1970) Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin: K. Terao; Acta Pathol. Jpn. 23, 647 (1973) Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin: P.T. Curry, et al.; Mutat. Res. 137, 111 (1984) Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bünger, et al.; Toxicology 202, 199 (2004) An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin: K.C. Ehrlich, et al.; Appl. Environ. Microbiol. 71, 8963 (2005) Aspergillus mycotoxins and their effect on the host: K. Kamei & A. Watanabe; Med. Mycol. 43, S95 (2005) A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ): D.S. Yao, et al.; Bioelectrochemistry 68, 126 (2006)

SDS

Datasheet/SDS