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PRL-3 Inhibitor (CAS 893449-38-2)

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Application:A cell permeable benzylidene rhodanine compound
CAS Number:893449-38-2
Purity:≥98%
Molecular Weight:485.2
Molecular Formula:C17H11Br2NO2S2
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
PRL-3 Inhibitor sc-222189 10 mg $280
Description
PRL-3 Inhibitor is a cell-permeable benzylidene rhodanine compound that potently inhibits hPRL-3, a member of the regenerating liver family tyrosine phosphatases. PRL-3 Inhibitor has been shown to reduce the invasiveness of murine melanoma B16F10 cells.
Technical Information
Appearance:Yellow
Physical State:Solid
Solubility:Soluble in DMSO (5 mg/ml). Slight warming may be necessary for complete solubilization.
Storage:Store at -20° C
Boiling Point:620.54 °C (Predicted)
Refractive Index:n20D 1.77 (Predicted)
IC50:hPRL-3 : IC50 = 900 nM
Safety and Reference Information
PubChem CID:11983303
SMILES:C1=CC=C(C(=C1)COC2=C(C=C(C=C2)Br)/C=C\3/C(=O)NC(=S)S3)Br
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Ahn, J.H., et al. 2006. Bioorg. Med. Chem. Lett. 16: 2996-2999. PMID: 16530413
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