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home » Transcription Regulators » CHRAC Antibody / CHRAC Antibodies » CHRAC15 (A-16): sc-21922

CHRAC15 (A-16) Antibody: sc-21922

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of CHRAC15 of mouse origin
  • recommended for detection of CHRAC15 of mouse, rat and, to a lesser extent, human origin by WB, IF and ELISA
  • blocking peptide, sc-21922 P
 
Additional CHRAC Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CHRAC1 54108 8q24.3 NM_017444 Q9NRG0
 607268
Mouse Chrac1 93696 15 D3 Q9JKP8
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CHRAC15 (A-16) sc-21922 200 µg/ml $279
CHRAC15 (A-16) P sc-21922 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CHRAC15 (N-18) sc-13457 200 µg/ml $279
CHRAC15 siRNA (m) sc-142335 10 µM $258
CHRAC15 (m)-PR sc-142335-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
 shRNA Lentiviral Particles (click product name for more information)
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CHRAC15 Background Information
DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators (1). CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex),which increases the accessibility of nucleosomal DNA in an ATP-dependent manner (2). Unlike other known chromatin remodelling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing (3). This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array (4). In the presence of CHRAC, the nucleosomal ATPase ISWI catalyses several ATP-dependent transitions of chromatin structure (5).