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p-PKA IIα reg Antibody (Ser 96)-R: sc-21901-R

 |  Datasheet

(Based on data analysis)
  • p-PKA IIα reg (Ser 96)-R Antibody is a rabbit polyclonal IgG provided at 200 µg/ml
  • recommended for detection of Ser 96 phosphorylated PKA IIα reg of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-21901 P
 

See additional PKA Antibodies including PKA, PKA alpha cat, PKA beta cat, PKA gamma cat, PKA I alpha reg, PKA I beta reg, PKA II alpha reg, PKA II beta reg and PKA Phosphopeptide Substrate.

Also see PKA Inhibitors, PKA Activators or PKA Substrates for functional analysis of cellular responses to PKA.


Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-PKA IIα reg (Ser 96) P sc-21901 P
(peptide)
 100 µg/0.5 ml $61
p-PKA IIα reg (Ser 96)-R Antibody sc-21901-R 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKA IIα reg siRNA (h) sc-39164 10 µM $258
PKA IIα reg siRNA (m) sc-39165 10 µM $258
PKA IIα reg (h)-PR sc-39164-PR 10 µM, 20 µl $23
PKA IIα reg (m)-PR sc-39165-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKA IIα reg shRNA Plasmid (h) sc-39164-SH 20 µg $520
PKA IIα reg shRNA Plasmid (m) sc-39165-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKA IIα reg shRNA (h) Lentiviral Particles sc-39164-V 200 µl $625
PKA IIα reg shRNA (m) Lentiviral Particles sc-39165-V 200 µl $625

The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme, resulting in release of active catalytic subunits. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus, where it phosphorylates the transcription factor cAMP response element binding protein (CREB) on Serine 133, which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the Pol II transcription initiation complex. Mouse Serine 96 (designated Ser 99 in human) is a phosphorylation site on the PKA IIå regulatory subunit.