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- mouse monoclonal IgG1; 200 µg/ml
- raised against mouse recombinant osteopontin
- recommended for detection of OPN of mouse, rat and human origin by WB, IP, IF and IHC(P)
- agarose conjugate for IP studies, OPN (AKm2A1) AC: sc-21742 AC, 500 µg/0.25 ml agarose
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OPN Background Information Osteopontin (OPN), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPN isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.
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See how others have used OPN (AKm2A1): sc-21742 antibody and or OPN (AKm2A1) antibody conjugates.
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OPN (AKm2A1)
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OPN (AKm2A1): sc-21742. Western blot analysis of mouse recombinant OPN.
OPN (AKm2A1): sc-21742. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human bone marrow showing cytoplasmic and extracellular staining.
OPN (AKm2A1): sc-21742. Western blot analysis of OPN expression in non-transfected: sc-117752 (A) and mouse OPN transfected: sc-122246 (B) 293T whole cell lysates.
OPN (AKm2A1): sc-21742. Western blot analysis of OPN expression in non-transfected: sc-117752 (A) and mouse OPN transfected: sc-122247 (B) 293T whole cell lysates.
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