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home » Kinases and Phosphatases » IKK Antibody / IKK Antibodies » p-IKKα/β (Thr 23): sc-21660

p-IKKα/β (Thr 23) Antibody: sc-21660

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml; also available as rabbit IgG, 200 µg/ml, sc-21660-R
  • epitope mapping to Thr 23 phosphorylated IKKα/β of human origin
  • recommended for detection of Thr 23 phosphorylated IKKα/β of mouse, rat and human origin by WB; also reactive with additional species, including canine, bovine, porcine and avian
  • blocking peptide, sc-21660 P
 
Additional IKK Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human IKBKB 3551 8p11.21 NM_001556 O14920
 603258
Mouse Chuk 12675 19 C3 Q60680
 N/A
Mouse Chuk 12675 19 C3 Q60680
 N/A
Mouse Ikbkb 16150 8 A2 O88351
 N/A
Mouse Ikbkb 16150 8 A2 O88351
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-IKKα/β (Thr 23) sc-21660 200 µg/ml $279
p-IKKα/β (Thr 23) P sc-21660 P
(peptide)
 100 µg/0.5 ml $61
p-IKKα/β (Thr 23)-R sc-21660-R 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IKKα siRNA (h) sc-29365 10 µM $258
IKKα siRNA (m) sc-29366 10 µM $258
IKKα (h)-PR sc-29365-PR 10 µM $23
IKKα (m)-PR sc-29366-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IKKα shRNA Plasmid (h) sc-29365-SH 20 µg $520
IKKα shRNA Plasmid (m) sc-29366-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IKKα shRNA (h) Lentiviral Particles sc-29365-V 200 µl $625
IKKα shRNA (m) Lentiviral Particles sc-29366-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa + TNFα Cell Lysate sc-2228 500 µg/200 µl $104

IKKα/β Background Information
The transcription factor NFkB is retained in the cytoplasm in an inactive form by the inhibitory protein IkB. Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB. IkB kinase å (IKKå) interacts with IkB-å and specifically phosphorylates IkB-å on the sites that trigger its degradation, serines 32 and 36. The functional IKK complex contains three subunits, IKKå, IKK∫ and IKK© (also designated NEMO), and each appear to make essential contributions to IkB phosphorylation. NFkB inducing kinase (NIK) phosphorylates IKKå at serine 176.

p-IKKα/β (Thr 23) Product Citations
See how others have used p-IKKα/β (Thr 23): sc-21660 antibody and or p-IKKα/β (Thr 23) antibody conjugates.


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