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BIS-Tris (CAS 6976-37-0)

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Synonym:2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol
Application:An inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant
CAS Number:6976-37-0
Purity:≥98%
Molecular Weight:209.2
Molecular Formula:C8H19O5N
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
BIS-Tris sc-216088 100 g $70
BIS-Tris sc-216088A 500 g $185
Description
BIS-Tris is an inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant with respect to temperature. Suitable for fractionation of hemoglobin. The useful pH range for the buffer is 5.8-7.2. Has a pKa of 6.5 at 25°C.
Technical Information
Appearance:White crystalline powder
Physical State:Solid
Solubility:Soluble in water (~209.2 g/l) at 20 °C, and alcohol.
Storage:Store at room temperature
Boiling Point:466.18 °C at 760 mmHg (Predicted)
Refractive Index:n20D 1.56 (Predicted)
Safety and Reference Information
WGK Germany:3
PubChem CID:81462
MDL Number:MFCD00002853
EC Number:230-237-7
Beilstein Registry:2205275
SMILES:C(CO)N(CCO)C(CO)(CO)CO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
Nealon, D.A., et al. 1980. Clin Chem. 26, 1516. Morin, L.G. 1977. Clin. Chem. 23, 1569.
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