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Trioxsalen (CAS 3902-71-4)

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Synonym:2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one; 4,5′,8-Trimethylpsoralen; TMP; Trisoralen
Application:A photochemical crosslinker of DNA used as a probe for nucleic acid structure
CAS Number:3902-71-4
Purity:99%
Molecular Weight:228.24
Molecular Formula:C14H12O3
Refer to Certificate of Analysis for lot specific data (including water content).
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Product NameCatalog #UnitPriceQtyAddFavorites
Trioxsalen sc-216017 1 g $47
Trioxsalen sc-216017A 5 g $186
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Description
Trioxsalen is a photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces.
Technical Information
Appearance:Powder
Physical State:Solid
Solubility:Methylene Chloride
Storage:Store at -20° C
Melting Point:229-231 °C (lit.)
Safety and Reference Information
Transport:UN 1759, Class 8, Packing group I
PubChem CID:5585
SMILES:CC1=CC(=O)OC2=C1C=C3C=C(OC3=C2C)C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
Shlyakhtenko, L.S., et al., Atomic force microscopy imaging of DNA covalently immobilized on a functionalized mica substrate. Biophys. J. 77, 568-576, (1999); G.D. Cimino Annu. Rev. Biochem. 54, 1151, (1985); Botta, R., and Gustavino, B., Relationship between chromatin bridges in anaphase and chromosomal aberrations induced by TMP + UVA (365 nm) in CHO cells. Mutat. Res. 374, 253-259, (1997); Mojica, F.J., and Higgins, C.F., Localized domains of DNA supercoiling: topological coupling between promoters. Mol. Microbiol. 22, 919, (1996);
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