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Leupeptin hydrochloride (CAS 24125-16-4)

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Application:A calpain, cysteine, and protease inhibitor
CAS Number:24125-16-4
Purity:≥95%
Molecular Weight:463.01
Molecular Formula:C20H38N6O4 HCl
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Leupeptin hydrochloride sc-215242 5 mg $59
Leupeptin hydrochloride sc-215242A 25 mg $205
Description
Leupeptins are produced by Actinomycetes and act as calpain, cysteine, and protease inhibitors. Studies show that Leupeptin preserves cardiac nitric oxide synthase 3 (NOS3) and has been used to study inner ear hair cells. Motorneuron degeneration studies have revealed that Leupeptin helps improve muscle function and motorneurons from cell death after nerve injury. We supply the Leupeptin Hydrochloride form.
Technical Information
Appearance:White to off-white powder
Physical State:Solid
Solubility:Soluble in water.
Storage:Store at -20° C
Boiling Point:734.4 °C at 760 mmHg (Predicted)
Safety and Reference Information
WGK Germany:3
PubChem CID:16219551
MDL Number:MFCD00133457
SMILES:CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C.Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Aoyagi, T., et al. 1969. J. Antibiot. 22: 283-286. PMID: 5810993
2. Kieran, D. and Greensmith, L. 2004. Neuroscience. 125: 427-439. PMID: 15062985
3. Momiyama, J., et al. 2006. Tohoku J. Exp. Med. 209: 89-97. PMID: 16707850
4. Lee, H.K., et al. 2009. Glia. 57: 1825-1834. PMID: 19455715
5. Papisova, A.I., et al. 2010. Biochimie. [Epub ahead of print]. PMID: 20868724
6. Muscari, C., et al. 2010. J. Surg. Res. 164: e27-e35. PMID: 20828747
7. Mauney, J., et al. 2010. Matrix Biol. [Epub ahead of print]. PMID: 20828613
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