Date published: 2026-6-10

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Benzidine dihydrochloride (CAS 531-85-1)

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Alternate Names:
4,4′-Diaminobiphenyl dihydrochloride
Application:
Benzidine dihydrochloride is a tumor promoting agent
CAS Number:
531-85-1
Purity:
≥99%
Molecular Weight:
257.16
Molecular Formula:
C12H12N22HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzidine dihydrochloride is a biaryl tumor promoter compound described in the induction of carcinogenesis in model organisms.


Benzidine dihydrochloride (CAS 531-85-1) References

  1. Factors modulating benzidine carcinogenicity bioassay.  |  Vesselinovitch, SD., et al. 1975. Cancer Res. 35: 2814-9. PMID: 1157051
  2. Role of N-glucuronidation in benzidine-induced bladder cancer in dog.  |  Babu, SR., et al. 1992. Carcinogenesis. 13: 1235-40. PMID: 1638692
  3. A safer and more sensitive substitute for diamino-benzidine in the light microscopic demonstration of retrograde and anterograde axonal transport of HRP.  |  Hardy, H. and Heimer, L. 1977. Neurosci Lett. 5: 235-40. PMID: 19605000
  4. A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride.  |  Levey, AI., et al. 1986. J Histochem Cytochem. 34: 1449-57. PMID: 2430010
  5. Proportional hazards regression of survival-sacrifice data with cause-of-death information in animal carcinogenicity studies.  |  Mao, L. 2019. Stat Med. 38: 3628-3641. PMID: 31074119
  6. Projections from the pretectal complex to the thalamic lateral dorsal nucleus of the cat.  |  Robertson, RT., et al. 1983. Exp Brain Res. 51: 157-71. PMID: 6194003
  7. Benzidine dihydrochloride: toxicological assessment in mice during chronic exposures.  |  Littlefield, NA., et al. 1983. J Toxicol Environ Health. 12: 671-85. PMID: 6366243
  8. The influence of sex, dose, time, and cross on neoplasia in mice given benzidine dihydrochloride.  |  Nelson, CJ., et al. 1982. Toxicol Appl Pharmacol. 64: 171-86. PMID: 7123548
  9. Sequential morphogenesis of liver tumors in mice given benzidine dihydrochloride.  |  Frith, CH., et al. 1980. Eur J Cancer (1965). 16: 1205-16. PMID: 7227447
  10. Carcinogenicity of benzidine, N,N'-diacetylbenzidine, and N-hydroxy-N,N'-diacetylbenzidine for female CD rats.  |  Morton, KC., et al. 1981. Carcinogenesis. 2: 747-52. PMID: 7285281

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzidine dihydrochloride, 1 g

sc-214584
1 g
$85.00

Benzidine dihydrochloride, 5 g

sc-214584A
5 g
$263.00