BJAB nuclear extract: sc-2145

The BJAB nuclear extract is derived from the BJAB cell line, a well-established model originating from a Burkitt's lymphoma, which is a type of non-Hodgkin's lymphoma. This cell line is composed of B lymphocytes and is frequently used to study B-cell physiology and the underlying mechanisms of lymphoma. The nuclear extract from BJAB cells contains a rich variety of nuclear proteins, including transcription factors, regulatory proteins, and chromatin-associated proteins that are crucial for understanding the gene regulatory networks within lymphocytes. Researchers utilize BJAB nuclear extracts to delve into the nuclear dynamics that govern B-cell behavior, particularly focusing on aspects like transcriptional regulation, DNA replication, and response to cellular stress. By examining these extracts, scientists can gain insights into the normal and pathological states of B cells, exploring how alterations in nuclear components can influence lymphoma progression. The BJAB nuclear extract has been instrumental in studies aimed at understanding the complex interactions within the nuclei of lymphoma cells, leading to a better understanding of gene expression patterns, signaling pathways, and the regulation of cell cycle and apoptosis in B lymphocytes.

BJAB nuclear extract References:

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