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ETAR Antibody (N-15): sc-21193

 |  Datasheet

(Based on data analysis)
  • ETAR Antibody (N-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of ETAR of human origin
  • recommended for detection of ETAR of human origin by WB, IF and ELISA; also reactive with additional species, including bovine
  • blocking peptide, sc-21193 P
  • See 4 citations for ETAR Antibody (N-15)
 

See additional ETAR Antibodies.

Also see ETAR Inhibitors for functional analysis of cellular responses to ETAR.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ETAR Antibody (N-15) sc-21193 200 µg/ml $279
ETAR (N-15) P sc-21193 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ETAR siRNA (h) sc-39960 10 µM $258
ETAR (h)-PR sc-39960-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ETAR shRNA Plasmid (h) sc-39960-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ETAR shRNA (h) Lentiviral Particles sc-39960-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human EDNRA 1909 4q31.23 NM_001957 P25101
 157300
 

Endothelin receptor A (ETAR), also known as EDNRA, ET1 Receptor, ETA, EDN1 and ET-AR is a member of the Guanine-binding regulatory protein-coupled receptor family. ETAR binds endothelins and has the highest affinity for its ligand ET1, as compared to the ETBR receptor. Both ET receptors, ETAR and ETBR, are activated by ET1, which results in inhibition of active lens sodium-potassium transport. Activation of the ET receptors also causes an increase in cytoplasmic calcium concentration in cultured lens epithelial cells. In addition, ETAR induces arachidonic acid accumulation. ETAR has seven hydrophobic transmembrane domains and is expressed in aorta, lung, atrium, kidney, placenta and prostate. Specifically, placental vascular smooth muscle cells (PVSMCs) exclusively express ETAR.

ETAR Antibody (N-15) Product Citations
See how others have used ETAR Antibody (N-15) and or ETAR Antibody (N-15) conjugates.


4 total citations
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