Molecular structure of Mabuterol, CAS Number: 56341-08-3
Mabuterol (CAS 56341-08-3)
Application:
Mabuterol is a β2-adrenergic agonist
CAS Number:
56341-08-3
Purity:
98%
Molecular Weight:
310.74
Molecular Formula:
C13H18ClF3N2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Mabuterol is a long acting β 2-adrenergic agonist which stimulates adenylyl cyclase activity and the closing of calcium channels. Studies indicate that the R enantiomer of Mabuterol is more potent than the S enantiomer. In addition, the half-life is longer in the R enantiomer than the S. Studies conducted on rats and dogs show that Mabuterol acts as a bronchodilator. These studies demonstrated that at high concentrations Mabuterol can also antagonize β1 adrenoceptors in guinea pigs.
Mabuterol (CAS 56341-08-3) References
- Enantioselective pharmacokinetics of mabuterol in rats studied using sequential achiral and chiral HPLC. | Lu, X., et al. 2005. Biomed Chromatogr. 19: 703-8. PMID: 16206140
- Simultaneous determination of β-agonists and psychiatric drugs in feeds by LC-MS-MS. | Suo, DC., et al. 2014. J Chromatogr Sci. 52: 604-8. PMID: 23817171
- Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog. | Akahane, K., et al. 1989. Br J Pharmacol. 97: 709-16. PMID: 2474351
- Analysis of 10 β-agonists in pork meat using automated dispersive pipette extraction and LC-MS/MS. | Mastrianni, KR., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1084: 64-68. PMID: 29571118
- Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca2+]i and mitochondrial fission/fusion. | Gu, Y., et al. 2019. Chem Biol Interact. 307: 63-72. PMID: 31009640
- Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice. | Evans, AK., et al. 2021. Neurobiol Aging. 106: 241-256. PMID: 34320462
- An ultrasensitive colloidal gold immunosensor to simultaneously detect 12 beta (2)-adrenergic agonists. | Xu, X., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1191: 123119. PMID: 35091293
- Analysis of β-agonists in Different Biological Matrices By Liquid Chromatography-tandem Mass Spectrometry. | Śniegocki, T., et al. 2021. J Vet Res. 65: 469-475. PMID: 35112001
- Enzyme immunoassay for mabuterol, a selective beta 2-adrenergic stimulant in the trachea. | Yamamoto, I., et al. 1985. J Immunoassay. 6: 261-76. PMID: 3900139
Inhibitor of:
GRK.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mabuterol, 10 mg | sc-211757 | 10 mg | $300.00 | |||
Mabuterol, 25 mg | sc-211757A | 25 mg | $540.00 |