Ethidium bromide monoazide (CAS 58880-05-0)

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Application:	A photoactive stain which binds covalently to nucleic acids in solution
CAS Number:	58880-05-0
Molecular Weight:	420.31
Molecular Formula:	C₂₁H₁₈BrN₅

Description

Ethidium bromide monoazide is a photoactive stain which binds covalently to nucleic acids in solution. Used to footprint drug binding sites on DNA, detect non-viable cells, identify ethidium binding sites on DNA and tRNA, and selectively inactivate gene expression.

Technical Information

Solubility:	Soluble in DMF or ethanol
Storage:	Store at -20° C
Fluoresence:	λex 461 nm, λem 624 nm

Safety and Reference Information

PubChem CID:	2762649
SMILES:	CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N=[N+]=[N-])N.[Br-]

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. McMurray, C.T., et al. 1991. Biochemistry. 30: 5644-5652. PMID: 2043608
2. Berns, M.W., et al. 2000. Proc. Natl. Acad. Sci. U.S.A. 97: 9504-9507. PMID: 10944219

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SDS

Datasheet/SDS