Date published: 2026-3-7

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Bromoacetic acid (CAS 79-08-3)

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Alternate Names:
2-Bromoacetic acid
Application:
Bromoacetic acid is used in organic synthesis
CAS Number:
79-08-3
Purity:
≥97%
Molecular Weight:
138.95
Molecular Formula:
C2H3BrO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bromoacetic acid, a halogenated organic compound, is extensively utilized in scientific research due to its unique reactivity and diverse applications. One of the primary mechanisms of action of bromoacetic acid lies in its ability to act as an alkylating agent, forming covalent bonds with nucleophilic groups in biomolecules such as proteins and nucleic acids. This property makes bromoacetic acid a valuable tool in bioconjugation strategies for labeling and modifying biomolecules, facilitating studies in fields such as proteomics, genomics, and chemical biology. Additionally, bromoacetic acid serves as a precursor in the synthesis of various organic compounds, including pharmaceutical intermediates, agrochemicals, and specialty chemicals. In organic synthesis, it is employed in the preparation of diverse functionalized molecules through its participation in reactions such as nucleophilic substitution, esterification, and amidation. Furthermore, bromoacetic acid derivatives find application in the synthesis of polymers and materials with tailored properties, contributing to advancements in fields like materials science and nanotechnology. Its versatility as a chemical reagent and precursor underscores its importance in scientific research, where it continues to enable discoveries and innovations across multiple disciplines.


Bromoacetic acid (CAS 79-08-3) References

  1. Human cell toxicogenomic analysis of bromoacetic acid: a regulated drinking water disinfection by-product.  |  Muellner, MG., et al. 2010. Environ Mol Mutagen. 51: 205-14. PMID: 19753638
  2. Ecotoxicology of bromoacetic acid on estuarine phytoplankton.  |  Gordon, AR., et al. 2015. Environ Pollut. 206: 369-75. PMID: 26247379
  3. Monohaloacetic acid drinking water disinfection by-products inhibit follicle growth and steroidogenesis in mouse ovarian antral follicles in vitro.  |  Jeong, CH., et al. 2016. Reprod Toxicol. 62: 71-6. PMID: 27151372
  4. Adsorption and purification performance of lysozyme from chicken egg white using ion exchange nanofiber membrane modified by ethylene diamine and bromoacetic acid.  |  Chang, YK., et al. 2021. Food Chem. 358: 129914. PMID: 34000689
  5. Synergistic cytotoxicity of bromoacetic acid and three emerging bromophenolic disinfection byproducts against human intestinal and neuronal cells.  |  Liu, J., et al. 2022. Chemosphere. 287: 131794. PMID: 34438205
  6. Bromoacetic acid induces neurogenic injury in the chicken brain by activating oxidative stress and NF-κB inflammatory pathway.  |  Liu, J., et al. 2022. Chem Biol Interact. 365: 110115. PMID: 35988748
  7. Bromoacetic acid causes oxidative stress and uric acid metabolism dysfunction via disturbing mitochondrial function and Nrf2 pathway in chicken kidney.  |  Wu, Y., et al. 2022. Environ Toxicol. 37: 2910-2923. PMID: 36017758
  8. Bromoacetic acid impairs mouse oocyte in vitro maturation through affecting cytoskeleton architecture and epigenetic modification.  |  Wang, YS., et al. 2022. Chem Biol Interact. 368: 110192. PMID: 36174739
  9. The gut microbiota metabolite glycochenodeoxycholate activates TFR-ACSL4-mediated ferroptosis to promote the development of environmental toxin-linked MAFLD.  |  Liu, S., et al. 2022. Free Radic Biol Med. 193: 213-226. PMID: 36265794
  10. Kinetics of inhibition of Penaeus penicillatus acid phosphatase by bromoacetic acid.  |  Chen, QX., et al. 1998. Biochem Mol Biol Int. 46: 215-23. PMID: 9801789

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bromoacetic acid, 100 g

sc-210962
100 g
$41.00

Bromoacetic acid, 500 g

sc-210962A
500 g
$102.00