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EG-VEGF Antibody (T-16): sc-21022

 |  Datasheet

(Based on data analysis)

  • EG-VEGF Antibody (T-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of EG-VEGF of human origin
  • recommended for detection of EG-VEGF of human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-21022 P
 

See additional VEGF Antibodies including VEGF, EG-VEGF, VEGF-B, VEGF-C and VEGF-D.

Also see VEGF Inhibitors for functional analysis of cellular responses to VEGF.


Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
EG-VEGF Antibody (T-16) sc-21022 200 µg/ml $279
EG-VEGF (T-16) P sc-21022 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
EG-VEGF siRNA (h) sc-45392 10 µM $258
EG-VEGF siRNA (h)-PR sc-45392-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
EG-VEGF shRNA Plasmid (h) sc-45392-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
EG-VEGF siRNA shRNA (h) Lentiviral Particles sc-45392-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PROK1 84432 1p13.3 NM_032414 P58294
606233
 


Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. EG-VEGF possesses an HIF-1 binding site; its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, testis, adrenal and placenta). Expression of EG-VEGF is often complementary to the expression of VEGF, suggesting that these molecules function in a coordinated manner. EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. It is expressed primarily in one type of tissue and acts selectively on one type of endothelium. EG-VEGF, possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation, migration and survival of responsive endothelial cells .